Results 141 to 150 of about 488,806 (353)

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

Advanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu, Yajing Liu, Shuman Wang, Xiaoming Bai, Luyun Zhang, Yuwei Liu, Zhiwen Fu, Chen Shi   +7 more
wiley   +1 more source

1377 Messenger RNA nanoparticles targeting fusion-driven malignancies

Journal for ImmunoTherapy of Cancer, 2023
Leighton Elliott, Hector Mendez-Gomez, Study Staff, Elias Sayour, Sadeem Qdaisat, Dingpeng Zhang   +5 more
doaj   +1 more source

Reactogenicity of the Messenger RNA SARS–CoV‐2 Vaccines Associated With Immunogenicity in Patients With Autoimmune and Inflammatory Disease

, 2022
Monica Yang, Kimberly E. Taylor, Diana Paez, Alex Carividi, Emanuel Demissie, Niti Pawar, Alia A. El‐Qunni, Lily E. McMorrow, Rebecca E. Schriefer, Katherine Huang, Baylee Kinnett, Michael K. Klebert, Alem Haile, Jane A. O’Halloran, Rachel M. Presti, Wooseob Kim, Ali H. Ellebedy, Matthew A. Ciorba, Michael Paley, Parakkal Deepak, Alfred H.J. Kim, Patricia Katz, Mehrdad Matloubian, Mary C. Nakamura, Lianne S. Gensler   +24 more
openalex   +2 more sources

Early vs Deferred Non–Messenger RNA COVID-19 Vaccination Among Chinese Patients With a History of Inactive Uveitis [PDF]

, 2023
Zhenyu Zhong, Qiuying Wu, Yuxian Lai, Lingyu Dai, Yu Gao, Weiting Liao, Guannan Su, Yao Wang, Chunjiang Zhou, Peizeng Yang   +9 more
openalex   +1 more source

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source

Bcl-2 and Bax Messenger RNA Gene Expression Detected by Reverse Transcriptase Polymerase Chain Reaction after Partial Hepatectomy and Licorice in Rats

, 2007
Rokaya Shalaby
openalex   +2 more sources

Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

Advanced Science, EarlyView.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang   +7 more
wiley   +1 more source

Messenger RNA-based vaccines: Past, present, and future directions in the context of the COVID-19 pandemic

, 2021
Samagra Jain, Abhijeet K. Venkataraman, Marissa E. Wechsler, Nicholas A. Peppas   +3 more
openalex   +2 more sources

Molecular Engineering Mediated Interfacial Assembly as an Artificial Extracellular Matrix Remolds Bacteria With Enhanced Abiotic Resilience

Advanced Science, EarlyView.
A biomimetic artificial extracellular matrix is assembled directly on Pseudomonas fluorescens by co‐assembling amyloid‐like lysozyme and alginate at the cell surface. This conformal nanocoating acts as both a hydration buffer and a physiological priming layer, markedly enhancing desiccation tolerance, seed adhesion, storage stability, and biocontrol ...
Yuanyuan Wang, Zili Jia, Yang Li, Qitao Wang, Shuai Hou, Lei Liu   +5 more
wiley   +1 more source

History of Micrornas: From Gene Controlling Development of Nematodes to a Promising Tool for Molecular Therapy

Acta Medica Martiniana
MicroRNAs are short, single-stranded RNA molecules that typically consist of a 22-nucleotide sequence. Despite their small size, these molecules play an essential role in every type of human cell – regulation of gene expression on post-transcriptional ...
Dusan Brany
doaj   +1 more source