Results 271 to 280 of about 1,529,458 (406)

Regulation of Chondrocyte Metabolism and Osteoarthritis Development by Sirt5 Through Protein Lysine Malonylation

open access: yesArthritis &Rheumatology, EarlyView.
Objective Chondrocytemetabolic dysfunction plays an important role in osteoarthritis (OA) development during aging and obesity. Protein posttranslational modifications (PTMs) have recently emerged as an important regulator of cellular metabolism. We aim to study one type of PTM, lysine malonylation (MaK), and its regulator sirtuin 5 (Sirt5) in OA ...
Huanhuan Liu   +11 more
wiley   +1 more source

Kinetics of avian vitellogenin messenger RNA induction. Comparison between primary and secondary response to estrogen.

open access: hybrid, 1977
R G Deeley   +4 more
openalex   +1 more source

Metamizole induces voriconazole metabolism and results in subtherapeutic voriconazole concentrations

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Voriconazole is extensively metabolized via cytochrome P450 (CYP) enzymes, predominantly CYP2C19 and CYP3A4. Drugs influencing the activity or expression of CYP enzymes can cause clinically relevant changes in the metabolism and voriconazole exposure. Metamizole is known to induce CYP3A4 and CYP2C19.
Simone D. Baan   +3 more
wiley   +1 more source

Translation of Synthetic Messenger RNA

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1966
Paul Doty   +4 more
openaire   +3 more sources

Annexin, a Protein for All Seasons: From Calcium Dependent Membrane Metabolism to RNA Recognition

open access: yesBioEssays, EarlyView.
Annexins are an important protein family traditionally well known to bind to phospholipids and to interact with various proteins in a calcium dependent way. More recently, it has been established that a feature common to the family is also to bind to RNA having a role in translation. In bies70019 article, Vedeler et al.
Anni Vedeler   +2 more
wiley   +1 more source

Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia

open access: yesCell Reports, 2017
D. An   +23 more
semanticscholar   +1 more source

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