Results 281 to 290 of about 1,529,458 (406)

Transcription‐Replication Conflicts: Unlocking New Frontiers in Cancer

BioEssays, EarlyView.
Transcription‐replication conflicts (TRCs) constitute a major source of genome instability. Such conflicts are regulated by chromatin, its dysfunction causing replication stress, DNA breaks, and mutations frequently found in cancer. We review the molecular basis of TRCs and chromatin regulation and discuss the clinical potential of targeting TRCs as ...
Aleix Bayona‐Feliu, Andrés Aguilera
wiley   +1 more source

Decreased Serum Insulin Receptor Messenger RNA Level in H. pylori IgG Seropositive Type 2 Diabetic Patients. [PDF]

Biomark Insights
Tagoe EA, Appiah JA, Boateng PA, Quaye O, Bosomprah S.   +4 more
europepmc   +1 more source

Mitochondrial Protein Synthesis: RNA with the Properties of Eukaryotic Messenger RNA

, 1973
Stanley Perlman, H T Abelson, Sheldon Penman   +2 more
openalex   +1 more source

Isolation of Polyribosomes and Messenger RNA Active in in Vitro Synthesis of Soybean Seed Proteins [PDF]

, 1978
Roger N. Beachy, John F. Thompson, James T. Madison   +2 more
openalex   +1 more source

N‐ to C‐Glycoside Rearrangement of Uridine 5′‐Phosphate in Two Enzymatic Steps for the Production of Pseudouridine 5′‐Phosphate

Biotechnology and Bioengineering, EarlyView.
The authors present a streamlined cascade reaction for one‐pot N‐C rearrangement of uridine‐5′‐phosphate (UMP) to pseudouridine‐5′‐phosphate (ΨMP; a key mRNA vaccine building block), in two enzymatic steps catalyzed by UMP nucleosidase (EC 3.2.2.10) and ΨMP C‐glycosidase (EC 4.2.1.70).
Martin Pfeiffer, Franziska Guld, Bernd Nidetzky   +2 more
wiley   +1 more source

Integrity assay for messenger RNA in mouse and human brain samples and synaptosomal preparations. [PDF]

iScience
Bujanauskiene D, Merkevicius K, Kuliesiute U, Denkovskij J, Kutanovas S, Luksys G, Rocka S, Bernotiene E, Neniskyte U.   +8 more
europepmc   +1 more source

Fate of Histone Messenger RNA in Synchronized HeLa Cells in the Absence of Initiation of Protein Synthesis [PDF]

, 1977
H. Stahl, Dieter Gallwitz
openalex   +1 more source

The contribution of extracellular RNA and its derived biomaterials in disease management

BMEMat, EarlyView.
The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei, Zhangyi Wang, Zixuan Qin, Qianqian Wan, Yutao Li, Franklin R. Tay, Chenyu Wang, Tong Zhang, Lina Niu   +8 more
wiley   +1 more source

Systemic messenger RNA replacement therapy is effective in a novel clinically relevant model of acute intermittent porphyria developed in non-human primates. [PDF]

Gut
Córdoba KM, Jericó D, Jiang L, Collantes M, Alegre M, García-Ruiz L, Manzanilla O, Sampedro A, Herranz JM, Insausti I, Martinez de la Cuesta A, Urigo F, Alcaide P, Morán M, Martín MA, Lanciego JL, Lefebvre T, Gouya L, Quincoces G, Unzu C, Hervas-Stubbs S, Falcón-Pérez JM, Alegre E, Aldaz A, Fernández-Seara MA, Peñuelas I, Berraondo P, Martini PGV, Avila MA, Fontanellas A.   +29 more
europepmc   +1 more source

A large product of cell-free translation of messenger RNA coding for corticotropin.

, 1976
Shigetada Nakanishi, Shunzo Taii, Yoko Hirata, Shigeru Matsukura, Hiroo Imura   +4 more
openalex   +1 more source