Results 311 to 320 of about 1,613,624 (375)

Mapping molluscan endocrinology: a systematic and critical appraisal

Biological Reviews, EarlyView.
ABSTRACT Historically, a vertebrate‐centric paradigm has framed our interpretation of molluscan endocrinology, with considerable research focusing on vertebrate‐type steroid hormones (e.g. oestrogens, testosterone). However, contradictory evidence on the occurrence of vertebrate‐type steroid hormones in molluscan tissues, and a lack of the specific ...
Konstantinos Panagiotidis, Thomas H. Miller, Olwenn V. Martin, Alice Baynes   +3 more
wiley   +1 more source

RNA m1A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stability and is a potential therapeutic target

Cancer Communications, EarlyView.
Abstract Background The role of N1‐methyladenosine (m1A) in cancer is poorly understood. Here we explored the function of RNA methyltransferase TRNA methyltransferase 61A (TRMT61A) in colorectal cancer (CRC) and its potential as a therapeutic target. Methods RNA m1A levels were assessed through liquid chromatography‐mass spectrometry.
Xiaoting Zhang, Na Qin, Fenfen Ji, Hao Su, Haiyun Shang, Hongyan Chen, Dan Huang, Qing Li, Jing Ren, Weixin Liu, Yifei Wang, Wei Kang, Jiabin Wu, Chi‐Chun Wong, Zongwei Cai, Matthew Tak Vai Chan, William Ka Kei Wu, Jun Yu, Huarong Chen   +18 more
wiley   +1 more source

Designing a multi-epitope construct using immuno-informatic tools to prepare a messenger RNA vaccine against Rhipicephalus microplus ticks. [PDF]

Vet World
Ullah U, Ashraf K, Shehzad W, Rashid MI.
europepmc   +1 more source

Safety and Immunogenicity of a Messenger RNA-Based Cytomegalovirus Vaccine in Healthy Adults: Results From a Phase 1 Randomized Clinical Trial. [PDF]

J Infect Dis
Fierro C, Brune D, Shaw M, Schwartz H, Knightly C, Lin J, Carfi A, Natenshon A, Kalidindi S, Reuter C, Miller J, Panther L.   +11 more
europepmc   +1 more source

Design, Synthesis, and Molecular Docking of Triazole‐Coumarin Hybrids as Potent Breast Cancer Inhibitors Targeting Cell Cycle and Apoptosis

Chemistry &Biodiversity, EarlyView.
Triazole‐coumarin hybrids were synthesized as breast cancer inhibitors. Derivative 5f induced S‐phase arrest and apoptosis in cancer cells, with minimal toxicity to healthy cells, showing promise for anticancer drug development. ABSTRACT Breast cancer continues to pose a significant global health burden, highlighting the urgent need for novel ...
Murat Keser, Emre Menteşe, Suleyman Ilhan, Mustafa Emirik, Harika Atmaca   +4 more
wiley   +1 more source

Optimized strategies for precise messenger RNA delivery using site-specific lipid nanoparticle-based drug delivery systems. [PDF]

Nanomedicine (Lond)
Cao W, Xia T.
europepmc   +1 more source

Optimizing Messenger RNA Analysis Using Ultra-Wide Pore Size Exclusion Chromatography Columns. [PDF]

Int J Mol Sci
D'Atri V, Lardeux H, Goyon A, Imiołek M, Fekete S, Lauber M, Zhang K, Guillarme D.   +7 more
europepmc   +1 more source

Exponential decline, ceiling effect, downregulation, and T-cell response in immunoglobulin G antibody levels after messenger RNA vaccine boosters: a case report. [PDF]

J Med Case Rep
Hirano H, Asada H.
europepmc   +1 more source

The Novavax Heterologous Coronavirus Disease 2019 Booster Demonstrates Lower Reactogenicity Than Messenger RNA: A Targeted Review. [PDF]

J Infect Dis
Marchese AM, Rousculp M, Macbeth J, Beyhaghi H, Seet BT, Toback S.   +5 more
europepmc   +1 more source

Pan‐cyclin‐dependent kinase inhibition is a potential treatment for adenoid cystic carcinoma that downregulates the MYB::NFIB fusion and induces tumor regression

Cancer Communications, EarlyView.
Junchi Huang, Peter Larsson, Maryam Kakay Afshari, Paloma Tejera Nevado, Tajana Tešan Tomić, André Fehr, Fredrik Jäwert, Göran Stenman, Mattias K. Andersson   +8 more
wiley   +1 more source