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Optimized strategies for precise messenger RNA delivery using site-specific lipid nanoparticle-based drug delivery systems. [PDF]
Nanomedicine (Lond)Cao W, Xia T.
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Optimizing Messenger RNA Analysis Using Ultra-Wide Pore Size Exclusion Chromatography Columns. [PDF]
Int J Mol SciD'Atri V +7 more
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Deconvoluting Lipid Nanoparticle Structure for Messenger RNA Delivery
Nano letters (Print), 2020Lipid nanoparticle (LNP) packaged mRNA vaccines have been deployed against infectious diseases such as COVID-19, yet their structural features remain unclear.
Yulia Eygeris +3 more
semanticscholar +1 more source
How Is Precursor Messenger RNA Spliced by the Spliceosome?
Annual Review of Biochemistry, 2019Splicing of the precursor messenger RNA, involving intron removal and exon ligation, is mediated by the spliceosome. Together with biochemical and genetic investigations of the past four decades, structural studies of the intact spliceosome at atomic ...
R. Wan, R. Bai, X. Zhan, Yigong Shi
semanticscholar +1 more source
EcoSal Plus, 2007
This chapter discusses several topics relating to the mechanisms of mRNA decay. These topics include the following: important physical properties of mRNA molecules that can alter their stability; methods for determining mRNA half-lives; the genetics and biochemistry of proteins and enzymes involved in mRNA decay; posttranscriptional ...
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This chapter discusses several topics relating to the mechanisms of mRNA decay. These topics include the following: important physical properties of mRNA molecules that can alter their stability; methods for determining mRNA half-lives; the genetics and biochemistry of proteins and enzymes involved in mRNA decay; posttranscriptional ...
openaire +2 more sources
Hormone inducible messenger RNA
Life Sciences, 1975Abstract Steroid hormones regulate the synthesis of specific proteins in target tissue by controlling the synthesis of the corresponding messenger RNA's. In the chick oviduct, estrogen and progesterone induce the synthesis and accumulation of the specific messenger RNA's for the hormone-induced egg-white proteins, ovalbumin and avidin, respectively ...
S L, Woo, B W, O'Malley
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Virology, 1974
Abstract Influenza viral messenger RNA (mRNA) free from both ribosomal RNA and newly synthesized host mRNA was isolated from the polyribosomes of infected canine kidney cells. Cordycepin was added to infected cells to inhibit ribosomal RNA and host mRNA synthesis.
P R, Etkind, R M, Krug
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Abstract Influenza viral messenger RNA (mRNA) free from both ribosomal RNA and newly synthesized host mRNA was isolated from the polyribosomes of infected canine kidney cells. Cordycepin was added to infected cells to inhibit ribosomal RNA and host mRNA synthesis.
P R, Etkind, R M, Krug
openaire +2 more sources