Results 191 to 200 of about 407,464 (291)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

A IMPORTÂNCIA PROGNÓSTICA DOS GRUPAMENTOS POUCO DIFERENCIADOS E BROTAMENTOS TUMORAIS NAS METÁSTASES HEPÁTICAS DO CÂNCER COLORRETAL

, 2017
Gilton Marques Fonseca, Evandro Sobroza de Mello, Sheila F. Faraj, Jaime Arthur Pirola Krüger, Fabrício Ferreira Coelho, Vagner Birk Jeismann, Paulo Herman, Ivan Cecconello   +7 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Mechanisms, Imaging Phenotypes, and Therapeutic Advances of Neovascularization in Brain Metastases. [PDF]

Biomedicines
Liu S, Shan B, Zhang Y, Xu L, Zhang X, Ye L, Diao H, Cheng Y, Tang J.   +8 more
europepmc   +1 more source

Terapêutica neo-adjuvante e adjuvante do cancro do reto [PDF]

, 2014
Adriano Manuel de Sousa Soares
core  

Redes neurais profundas e aprendizagem de máquina aplicados na diferenciação de tumores pulmonares primários de metástases em exames de tomografia computadorizada [PDF]

Letícia de Souza Barcellos Lima
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Anal Squamous Cell Carcinoma with Bilateral Renal Metastases: A Rare Presentation with Literature Review. [PDF]

Curr Oncol
Gul K, Kamatham S, Chiriboga G, Abdelhakeem A, Nassar A, O'Donnell C, Majeed U.   +6 more
europepmc   +1 more source

Tumores Neuroendócrinos do reto: do diagnóstico à terapêutica [PDF]

, 2014
Narcisa Flôr Rodrigues Pinto Guimarães
core  

ANÁLISE DE SOBREVIDA EM PACIENTES COM CÂNCER DE COLO DO ÚTERO COM METÁSTASES EXCLUSIVAS PARA LINFONODOS PARA-AÓRTICOS

, 2017
Karla Fabiane Siebra de Oliveira Maia, Nuno Vaz, Maria Del Pilar Estevez-Diz, Vanessa da Costa Miranda   +3 more
openalex   +1 more source