Results 221 to 230 of about 413,432 (237)

First-Line Alectinib Versus Ceritinib With or Without Brain Radiotherapy in ALK-Positive Non-Small Cell Lung Cancer with Brain Metastases: A Real-World Multicenter Study from Vietnam. [PDF]

Thorac Cancer
Nguyen HG, Nguyen XH, Nguyen P, Nguyen TH, Vinh QB.   +4 more
europepmc   +1 more source

Small Extracellular Vesicles‐Derived Circ6718 Unlocks Stromal Remodeling and Serves as a Biomarker in Gastric Cancer

Advanced Science, EarlyView.
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang, Xueyan Zang, Dongli Wang, Rong Li, Hui Qian, Wenrong Xu, Jiajia Jiang, Yongmin Yan   +7 more
wiley   +1 more source

Liquid biopsy-based genomic risk score to predict neurologic death in non-small cell lung cancer patients. [PDF]

J Neurooncol
Glynn SE, D'Agostino R, Lanier CM, R Choi A, Farris M, Abdulhaleem M, Young P, Wang Y, Smith M, Ruiz J, Lycan T, Petty WJ, Cramer CK, Tatter SB, Laxton AW, White JJ, Su J, T Whitlow C, Xing F, Chan MD, Helis CA.   +20 more
europepmc   +1 more source

Cancer‐Associated Fibroblasts Promote Tumor Immunosuppression in Hepatocellular Carcinoma via the NNMT‐ANGPTL4 Axis

Advanced Science, EarlyView.
ABSTRACT Background & Aims: Cancer‐associated fibroblasts (CAFs) drive immunosuppression in hepatocellular carcinoma (HCC). However, their metabolic regulation remains poorly defined. We investigated the role of nicotinamide N‐methyltransferase (NNMT) in CAFs. Approach & Results: High NNMT expression in CAF tissues was confirmed by western blotting and
Shounan Lu, Shanjia Ke, Hongjun Yu, Zhanzhi Meng, Miaoyu Bai, Yanan Xu, Hui Zhu, Jinwen Yang, Baolin Qian, Bing Yin, Chaoqun Wang, Zhigang Feng, Zhongyu Li, Yongzhi Zhou, Zihao Li, Xinglong Li, Yongliang Hua, Yao Fu, Wei Tang, Yaohua Wu, Yong Ma   +20 more
wiley   +1 more source

Whole-body magnetic resonance imaging vs. positron emission tomography-computed tomography in pediatric oncology: enhancing diagnostic precision for solid tumors. [PDF]

Rev Assoc Med Bras (1992)
Görkem SB, Çıkman G.
europepmc   +1 more source

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source

Intra-arterial Chemoperfusion for Lung Cancer Brain Metastases. [PDF]

Cureus
Vogl TJ, Stein LV, Adwan H.
europepmc   +1 more source

Dural-based melanoma metastasis mimicking a posterior fossa meningioma: A case report and review of the literature. [PDF]

Surg Neurol Int
Raffa PEAZ, Filho JLQ, Melo GO, de Oliveira AA, Santana HF, Brassarola PHA, Cunali AB, Pissolato TO, Aguiar PHP, Caramanti RL.   +9 more
europepmc   +1 more source

Prognostic Factors for Intracranial Progression in Her-2-Overexpressing Breast Cancer Patients with Brain Metastases as Primary Relapse Site-Real-Life Data. [PDF]

Cancers (Basel)
Majewska A, Byrski T, Falco M.
europepmc   +1 more source

Tailored management of a melanoma patient with bleeding brain metastases and deep vein thrombosis with thrombectomy. [PDF]

CNS Oncol
Viterbo A, De Angelis F, Ceccarelli C, Arezzini L, Del Roscio D, Pastina I, Pieraccini M.   +6 more
europepmc   +1 more source