Results 181 to 190 of about 805,322 (205)

Metabolic dysfunction-associated steatotic liver disease accelerates pancreatic cancer progression and metastasis via the macrophage migration inhibitory factor-CD44 axis. [PDF]

Signal Transduct Target Ther
Yu Q, Song H, Shi XY, Zhu L, Liang Y, Gong RN, Dong XW, Liu SL, Wang HZ, Wang YL, Cui JF, Yang XN, Chen Y, Gao C, Yang Z, Zhu QT, Li C, Zhang H, Ying JE, Zheng MF, Tian YT, Hu HT, Shao XX, Li Y, Mo MG, Lu Y, Ma Z, Fu SL, Niu QH, Liao YY, Zhao CY, Liu X, Saluja AK, Wang JG, Li XY, Guo SY, Wang WH, Wang S, Liu B, Lu GT, Ren H.   +40 more
europepmc   +1 more source

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

Advanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro, Margarida Henriques‐Pereira, Bruno M. Neves, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

A novel tool to predict the probability of pulmonary metastasis in patients with primary osseous sacral/pelvic tumors: a large real-world multicenter study. [PDF]

BMC Pulm Med
Zhou Z, Chen S, Huang Z, Yang B, Zhao Z, Chen K, Dai P.   +6 more
europepmc   +1 more source

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source

Bioengineered Lymphatic Vessels in Synthetic Matrices to Study Breast Cancer Cell Functions

Advanced Healthcare Materials, EarlyView.
Lymphatic vessels are involved in cancer metastasis. To study the interplay between metastasizing cancer cells and lymphatic vessels under highly reproducible conditions, advanced in vitro models are required. In this work, 3D lymphatic networks are formed in biomimetic hydrogels and their interactions with invasive and non‐invasive cancer cell‐lines ...
Rodi Odabasi, Lisa A. Krattiger, Magdalini Kanari, Mira A. Jacobs, Lukas O. Moser, Mark W. Tibbitt, Cornelia Halin, Martin Ehrbar   +7 more
wiley   +1 more source

Metastatic disease in conjunctival malignant melanoma: a retrospective analysis of 167 cases. [PDF]

BMJ Open Ophthalmol
Sezgin M, Rahal A, Nowack V, Manthey A, Suesskind D, Guberina M, Stuschke M, Flühs D, Sauerwein WAG, Griewank K, Schadendorf D, Herault J, Bechrakis NE, Westekemper H.   +13 more
europepmc   +1 more source

Geometrical Designs in Volumetric Bioprinting to Study Cellular Behaviors in Engineered Constructs

Advanced Healthcare Materials, EarlyView.
Curvature and spatial confinement guide cell behavior in volumetrically printed 3D constructs. Endothelial cells align and spread along specific geometries, while metastatic osteosarcoma cells proliferate independently of structural cues. Label‐free holographic microscopy captures real‐time, long‐term cell–material interactions, highlighting Gel‐PEG's ...
Julia Simińska‐Stanny, Pierre Tournier, Armin Shavandi, Shukry J Habib   +3 more
wiley   +1 more source

Oncological Outcomes and Genomic Features of Gastric-Type Endocervical Adenocarcinoma, the Most Aggressive and Common HPV-Independent Cervical Cancer. [PDF]

Cancers (Basel)
Du M, Zheng Z, Lu P, Wang W, Cao D, Yang J, Wu M, Pan L, Xue X, Wang W, Jiang F, Xiang Y.   +11 more
europepmc   +1 more source