Results 11 to 20 of about 17,702 (230)

Patient‐Reported Outcomes with Selpercatinib Treatment Among Patients with RET‐Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO‐001 Trial

open access: yesThe Oncologist, EarlyView., 2021
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth   +10 more
wiley   +1 more source

Histological and Immunohistochemical Characterization of a Histiocytic Sarcoma Associated With a Follicular Lymphoma in a Ring-tailed Lemur (Lemur catta). [PDF]

open access: yesVet Med Sci
Histological and Immunohistochemical Characterization of a Histiocytic Sarcoma Associated with a Follicular Lymphoma in a Ring‐tailed Lemur (Lemur catta). Nicolás Aradilla, Rocío Canales, Teresa Lorenzo‐Bermejo, Mireia Mainez, Jordi Aguiló‐Gisbert, David Marbella, Javier María De Pablo‐Moreno and Antonio Rodríguez‐Bertos.
Aradilla N   +7 more
europepmc   +2 more sources

Melanoma metastásico a vejiga

open access: yesMedUNAB, 2021
RESUMEN Introducción. El compromiso tumoral metastásico del melanoma al tracto genitourinario es frecuente, pero, la metástasis a vejiga es rara, constituye menos del 2% de los casos.
Ana María Ortiz-Zableh   +4 more
doaj   +1 more source

Metástasis gingival de adenocarcinoma de colon [PDF]

open access: yes, 2006
La cavidad oral es lugar de asiento de tumores metastásicos, sobre todo con origen en mama y pulmón. La mayoría de los casos afectan por este orden a los huesos mandibular y maxilar, aunque en ocasiones se desarrollan sobre las partes blandas intraorales.
Delgado Sánchez-Gracián, Carlos   +3 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Características clínico-patológicas del adenocarcinoma gástrico en el servicio de patología en el Hospital Escuela Dr. Roberto Calderón Gutiérrez del Enero 2012 hasta Diciembre 2014 [PDF]

open access: yes, 2015
Con el fin de establecer la correlación clínica - histopatológica de los adenocarcinomas gástricos diagnosticados en el Hospital Escuela Dr. Roberto Calderón Gutiérrez, se realizó un estudio en el periodo comprendido desde enero 2012 a diciembre 2014, se
Ruíz Almanza, Daniel
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Colorectal cancer carcinogenesis [PDF]

open access: yes, 2012
El cáncer colorrectal representó en el año 2008 el tercer tumor más diagnosticado en España, siendo la segunda neoplasia que causó más fallecimientos. El conocimiento del proceso carcinogenético de este tipo de enfermedad permitirá el descubrimiento de
Menéndez Sánchez, Pablo   +4 more
core   +1 more source

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

open access: yesAdvanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro   +4 more
wiley   +1 more source

Tumores testiculares caninos : a propósito de dos casos clínicos [PDF]

open access: yes, 2010
Los tumores testiculares tienen una mayor incidencia en la especie canina que en otras especies y son una patología habitual en la clínica diaria, aunque generalmente son hallazgos de la exploración física.
Cloquell, A.   +3 more
core   +1 more source

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