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Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source

Continuing education of non-Polish citizens according to Polish law [PDF]

Edukacja Ustawiczna Dorosłych, 2018
The issue of lifelong learning occupies a prominent position in the education system. Adults, for various reasons, undertake education, which is part of the lifelong learning trend. Foreigners are a special group.
Magdalena Pyter
doaj

Gynecological and obstetric interventions in the emergency medical service in Poland during the COVID-19 pandemic: a pilot study.

Critical Care Innovations, 2022
INTRODUCTION: : Functioning of the EMS during one year pre-pandemic compared to one year pandemic outbreak was analysed in relation to specific intervention groups alongside each other.
Łukasz Dudziński +3 more
doaj +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk +10 more
wiley +1 more source

The impact of migration related to the conflict in Ukraine on the management of social policy in Poland

Journal of Modern Science
Objectives The aim of the article is to analyze the impact of migration related to the conflict in Ukraine on the management of social policy in Poland and to assess to what extent the Polish social policy system has met the challenges resulting from ...
Zbigniew Ciekanowski +2 more
doaj +1 more source

The Mesoscale Convective Systems with bow echo radar signatures as an example of extremely severe and widespread geohazard in Poland

Environmental & Socio-economic Studies, 2018
In the last two decades we can notice a significant increase of severe anemological events, which are mostly connected with mesoscale convective systems and a cold front of a deep low-pressure system.
Widawski Artur, Pilorz Wojciech
doaj +1 more source

A need to implement new tools for diagnosing tobacco-addition syndrome and readiness/motivation to quit smoking in the working-age population in Poland

Medycyna Pracy, 2016
High rates of tobacco use is still observed in working-age population in Poland. The present level of the state tobacco control has been achieved through adopting legal regulations and population-based interventions.
Marzenna Broszkiewicz, Wojciech Drygas
doaj +1 more source

Acetoacetates Derived From Vegetable Oils: A Platform for Tailor‐Made Vinylogous Urethane Foams

Advanced Functional Materials, EarlyView.
A renewable vegetable oil is converted into acetoacetate‐functionalized precursors for the preparation of catalyst‐free vinylogous urethane foams. Room‐temperature foaming with n‐pentane generates lightweight cellular materials, while the choice of amine enables control over foam structure and mechanical properties.
Krzysztof Polaczek +8 more
wiley +1 more source

maritime education and training met
gdynia maritime university gmu
stcw convention