Results 71 to 80 of about 1,483,696 (298)

CSF and blood levels of Neurofilaments, T-Tau, P-Tau, and Abeta-42 in amyotrophic lateral sclerosis: a systematic review and meta-analysis

Journal of Translational Medicine
Recent literature suggests that markers of neuroaxonal damage, such as neurofilaments and tau protein, might serve as potential biomarkers for ALS. We conducted this systematic review and meta-analysis study to compare cerebrospinal fluid (CSF) and blood
Elmira Agah, Helia Mojtabavi, Atefeh Behkar, Arash Heidari, Atra Ajdari, Zoha Shaka, Seyed Vahid Mousavi, Negar Firoozeh, Abbas Tafakhori, Nima Rezaei   +9 more
doaj   +1 more source

Treatment options for women with heavy menstrual bleeding: a protocol for comprehensive systematic review, network meta-analyses and health economic assessment

BMJ Open
Introduction A quarter of women experience heavy periods in their lifetime, often significantly impairing their well-being, productivity and quality of life.Several treatment options are offered for heavy menstrual bleeding; however, there is limited ...
Rachael M Hunter, Ewelina Rogozinska, Claire L Vale, Khalid Saeed Khan, David J Fisher, Bassel H Al Wattar, Davor Jurkovic, Ngawai Moss, Jayne F Tierney, Ekaterina Bordea, Niccola Hutchinson-Pascal, Lily Nicholson   +11 more
doaj   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Exploring the pharmacological versatility of ficus carica: Modulating classical immunometabolism and beyond

Pharmacological Research, 2023
The burden of metabolic disorders is alarmingly increasing globally. On the other hand, sustainability is the key project of the 21st century. Natural products offer a coherent option for the complementary management of both these challenges.
Amene Saghazadeh
doaj  

The effect of partially exposed connective tissue graft on root‐coverage outcomes: a systematic review and meta‐analysis

European Journal of Oral Sciences, 2018
The aim of this systematic review was to compare the root‐coverage outcomes of using a partially exposed connective tissue graft (CTG) technique with a fully covered CTG technique for root coverage. An electronic search up to February 28th, 2017, was performed to identify human clinical studies with data comparing outcomes of root coverage using CTG ...
Yu Lin Lai, Moawia M. Kassab, Jeffrey Garcia, Paul G. Luepke, Guo-Hao Lin, Guo-Hao Lin, Austin Dodge   +6 more
openaire   +4 more sources

A meta‐analysis of the relation between therapeutic alliance and treatment outcome in eating disorders [PDF]

International Journal of Eating Disorders, 2017
AbstractThe therapeutic alliance has demonstrated an association with favorable psychotherapeutic outcomes in the treatment of eating disorders (EDs). However, questions remain about the inter‐relationships between early alliance, early symptom improvement, and treatment outcome. We conducted a meta‐analysis on the relations among these constructs, and
Graves, Tiffany A, Tabri, Nassim, Thompson-Brenner, Heather, Franko, Debra L, Eddy, Kamryn T, Bourion-Bedes, Stephanie, Brown, Amy, Constantino, Michael J, Flückiger, Christoph, Forsberg, Sarah, Isserlin, Leanna, Couturier, Jennifer, Paulson Karlsson, Gunilla, Mander, Johannes, Teufel, Martin, Mitchell, James E, Crosby, Ross D, Prestano, Claudia, Satir, Dana A, Simpson, Susan, Sly, Richard, Lacey, J Hubert, Stiles-Shields, Colleen, Tasca, Giorgio A, Waller, Glenn, Zaitsoff, Shannon L, Rienecke, Renee, Le Grange, Daniel, Thomas, Jennifer J   +28 more
openaire   +8 more sources

The burden of intracranial atherosclerosis on cerebral small vessel disease: A community cohort study

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Exploring the prevalence and association between intracranial atherosclerosis (ICAS) and cerebral small vessel diseases (CSVD), this study delved beyond the current scope, utilising high‐resolution vessel wall MRI (HRVW‐MRI) to investigate how subtle changes in intracranial atherosclerotic features influence the various burdens of ...
Joseph Amihere Ackah, Heng Du, Wenjie Yang, Huixing Zeng, Jason Tsz Lok Chan, Michael Lung Cheung Lo, Xiangyan Chen   +6 more
wiley   +1 more source

Estimation of novel coronavirus (COVID‐19) reproduction number and case fatality rate: A systematic review and meta‐analysis

Health Science Reports, 2021
Background and aims Realizing the transmission potential and the magnitude of the coronavirus disease 2019 (COVID‐19) aids public health monitoring, strategies, and preparation.
Tanvir Ahammed, Aniqua Anjum, Mohammad Meshbahur Rahman, Najmul Haider, Richard Kock, Md Jamal Uddin   +5 more
doaj   +1 more source

HR-pQCT Measures of Bone Microarchitecture Predict Fracture: Systematic Review and Meta-Analysis [PDF]

Journal of Bone and Mineral Research, 2019
ABSTRACT High-resolution peripheral quantitative computed tomography (HR-pQCT) is a noninvasive imaging modality for assessing volumetric bone mineral density (vBMD) and microarchitecture of cancellous and cortical bone. The objective was to (1) assess fracture-associated differences in HR-pQCT bone parameters; and (2) to determine if HR-
Anthony Hall, Amaka C. Offiah, Suzanne N Morin, Jay R. Shapiro, Nicholas Mikolajewicz, Nicholas Mikolajewicz, Andrew J. Burghardt, Pauline T. Lukey, Svetlana V. Komarova, Svetlana V. Komarova, Nick Bishop, Kenneth M. Kozloff, Lars Folkestad, Kim Wager, Francis H. Glorieux, Bert van Rietbergen, Bettina M. Willie, Bettina M. Willie, Michael Molloy-Bland   +18 more
openaire   +8 more sources

Nuclei‐Specific Amygdala Enlargement Is Linked to Psychiatric Comorbidities in Drug‐Resistant Focal Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amygdala enlargement has been the subject of controversial studies regarding its significance in terms of pathogenicity both in epilepsy and in psychiatric comorbidities such as anxiety, depression, and post‐traumatic stress disorder.
Hélène Mourre, Julia Makhalova, Lisa Soncin, Elodie Garnier, Hugo Dary, Arnaud Le Troter, Roy A. M. Haast, Benoit Testud, Marie Arthuis, Samuel Medina Villalon, Stanislas Lagarde, Francesca Pizzo, Christian Bénar, Jean‐Philippe Ranjeva, Maxime Guye, Fabrice Bartolomei   +15 more
wiley   +1 more source