Meta‐analysis has been recognized as the best means to evaluate objectively and study the evidence for a particular issue. In order to give researchers a better understanding of the Meta process, we present an overall introduction to Meta‐analysis in ...
Xu Fang, Nan Zhao, Zhao‐Qiong Zhu
doaj +1 more source
Karl Pearson's meta-analysis revisited [PDF]
This paper revisits a meta-analysis method proposed by Pearson [Biometrika 26 (1934) 425--442] and first used by David [Biometrika 26 (1934) 1--11]. It was thought to be inadmissible for over fifty years, dating back to a paper of Birnbaum [J.
Owen, Art B.
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Meta-analysis and systematic review of skin graft donor-site dressings with future guidelines. [PDF]
Background: Many types of split-thickness skin graft (STSG) donor-site dressings are available with little consensus from the literature on the optimal dressing type. The purpose of this systematic review was to analyze the most recent outcomes regarding
Alwaal+58 more
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Estimates of heterogeneity (I2) can be biased in small meta-analyses [PDF]
In meta-analysis, the fraction of variance that is due to heterogeneity is known as I2. We show that the usual estimator of I2 is biased. The bias is largest when a meta-analysis has few studies and little heterogeneity.
von Hippel, Paul T.
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META – ANALYSIS FOR AGRICULTURAL RESEARCHES (REVIEW) [PDF]
This article aimed to discuss the Meta- analysis and its use in agricultural research. This analysis carefully reviews the results that have already been published; it works on organizing, integrating and scientific evaluation of previous researches and ...
Eskander H. alqysy+2 more
doaj +1 more source
Belimumab : a technological advance for systemic lupus erythematosus patients? Report of a systematic review and meta-analysis [PDF]
Objectives: To undertake a systematic review and meta-analysis to investigate clinical effectiveness of belimumab for patients with systemic lupus erythematosus (SLE) and antinuclear and/or anti-double-stranded DNA (dsDNA) autoantibodies.
Clarke, Aileen+9 more
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Misleading meta-analysis [PDF]
A meta-analysis of treatments in myocardial infarction published in 1992 retrospectively showed that streptokinase was associated with a highly significant fall in mortality by 1977, after inclusion of 15 trials.1 Thrombolysis was, however, not widely recommended until 10 years later—after the effect was confirmed in two mega trials.1 2 3 In the case ...
George Davey Smith, Matthias Egger
openaire +3 more sources
Heart failure with mid-range ejection fraction in CHARM: characteristics, outcomes and effect of candesartan across the entire ejection fraction spectrum. [PDF]
AIMS: We tested the hypothesis that candesartan improves outcomes in heart failure (HF) with mid-range ejection fraction [HFmrEF; ejection fraction (EF) 40-49%].
Borlaug+25 more
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Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Bone mineral density and fracture risk with long-term use of inhaled corticosteroids in patients with asthma: systematic review and meta-analysis [PDF]
Objectives: We aimed to assess the association between long-term use of inhaled corticosteroids (ICS) and bone adverse effects in patients with asthma. Design: Systematic review and meta-analysis of fracture risk and changes in bone mineral density with ...
Agertoft+32 more
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