Results 41 to 50 of about 17,266,935 (304)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

PERANCANGAN VISUAL PLANNING (VP) UNTUK PERBAIKAN PENCAPAIAN QUALITY OBJECTIVE (QO) DI DIREKTORAT PRODUKSI PT. KRAKATAU WAJATAMA

open access: yes, 2018
AbstrakKinerja PT. Krakatau Wajatama sebagai salah satu perusahaan pengolahan baja Long Product dipengaruhi oleh faktor Ekternal yaitu Kurs Dolar Amerika, kebutuhan baja domistik, dan faktor Internal yaitu biaya produksi.
Mardono, untung
core   +1 more source

MANFAAT METODE INQUIRY TERHADAP PENGAMATAN HASIL PRAKTIKUM LAS LISTRIK DI LABORATORIUM MANUFAKTUR POLITEKNIK META INDUSTRI CIKARANG

open access: yes, 2022
The purpose of this study was to determine student achievement in the manufacturing process subject before giving treatment, to determine student achievement in the manufacturing process course after treatment, to determine whether there was an effect of
Rivandi, Merdieco, Widodo, Agus
core   +1 more source

Effectiveness of non-technical skills training in intensive care units: a systematic review

open access: yesBMC Medical Education
Background Non-technical skills (NTS) are social, cognitive and psychological skills that are related to safety and efficiency in the healthcare process. These skills have an important role in the intensive care once are closely related to the occurrence
Isac Davidson Santiago Fernandes Pimenta   +9 more
doaj   +1 more source

Meta-Analysis of Prognostic Role of Ki-67 Labeling Index in Gastric Carcinoma

open access: yesThe International Journal of Biological Markers, 2017
Background This meta-analysis aimed to elucidate the prognostic role of the Ki-67 labeling index (LI) in gastric cancer (GC). Methods The current study included 3,615 GC patients in 20 eligible studies, and evaluated the prognostic role of Ki-67 LI in GC.
Jung-Soo Pyo, Nae Yu Kim
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Informe de práctica empresarial

open access: yes, 2023
Informe de práctica profesional del programa de Comunicación Social y PeriodismoEl 9 de noviembre de 1982, en el barrio El Triunfo de la ciudad de Villavicencio, se reunieron Rafael Mojica García, Nancy Leonor Espinel Riveros y Ramiro Mojica García ...
Vélez Barrera, Jhon Oscar
core  

A parametric meta‐analysis

open access: yesStatistics in Medicine, 2019
In a meta‐analysis, we assemble a sample of independent, nonidentically distributed p‐values. The Fisher's combination procedure provides a chi‐squared test of whether the p‐values were sampled from the null uniform distribution. After rejecting the null uniform hypothesis, we are faced with the problem of how to combine the assembled p‐values.
Chang Yu, Daniel Zelterman
openaire   +4 more sources

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