Results 31 to 40 of about 3,253,095 (322)

Cardiovascular risk factors, global cardiovascular risk, and vascular age in a cohort of Peruvian HIV patients

HIV & AIDS Review. International Journal of HIV-Related Problems
Introduction Data on cardiovascular risk and vascular age in patients with human immunodeficiency virus (HIV) from developing countries are scarce. Therefore, the current study aimed to determine the prevalence of cardiovascular risk factors, global ...
German Valenzuela-Rodriguez, Jaime A. Collins, Raul Castillo, Luis R. Illescas, Adrian V. Hernandez, Carlos Diaz-Arocutipa   +5 more
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Meta-Analysis of the Relationship Between Ethnicity, Obesity, and Type 2 Diabetes of Adults in Urban Populations of Central America [PDF]

, 2016
The purpose of this meta-analysis was to examine the impact of ethnicity and obesity as it relates to Type-2 Diabetes (T2D) in specific Central American countries. A meta-analysis was conducted to determine the association of ethnicity, obesity, and T2D.
Humphries, J. (James), Johnson, J. A. (James), Samuel, C. (Cheryl), Wuenstel, W. G. (William)   +3 more
core  

Hybrid copula mixed models for combining case-control and cohort studies in meta-analysis of diagnostic tests [PDF]

, 2016
Copula mixed models for trivariate (or bivariate) meta-analysis of diagnostic test accuracy studies accounting (or not) for disease prevalence have been proposed in the biostatistics literature to synthesize information.
Aas K, Aristidis K Nikoloulopoulos, Brenner H, Chen Y, Chen Y, Chu H, Chu H, Demidenko E, Jerant A, Joe H, Joe H, Joe H, Joe H, Kurowicka D, Leeflang MM, Leeflang MMG, Ma X, Nash J, Nelsen RB, Nikoloulopoulos AK, Nikoloulopoulos AK, Nikoloulopoulos AK, Nikoloulopoulos AK, Sklar M, Stober J, Stroud AH, Varin C, Varin C, Xing Y   +28 more
core   +2 more sources

Effectiveness of non-technical skills training in intensive care units: a systematic review

BMC Medical Education
Background Non-technical skills (NTS) are social, cognitive and psychological skills that are related to safety and efficiency in the healthcare process. These skills have an important role in the intensive care once are closely related to the occurrence
Isac Davidson Santiago Fernandes Pimenta, Ádala Nayana de Sousa Mata, Isaac Newton Machado Bezerra, Rícia Medeiros Palmeira de Araújo, Jorge Lucas Alves Santana, Helaine Carneiro Capucho, Adriana Catarina de Souza-Oliveira, Paloma Echevarría-Pérez, Daniel Guillén-Martínez, Grasiela Piuvezam   +9 more
doaj   +1 more source

Cytoreductive surgery (CRS) with hyperthermic intraoperative peritoneal chemotherapy (HIPEC) versus standard of care (SoC) in people with peritoneal metastases from colorectal, ovarian or gastric origin: protocol for a systematic review and individual participant data (IPD) meta-analyses of effectiveness and cost-effectiveness

BMJ Open, 2020
Introduction There is uncertainty about whether cytoreductive surgery (CRS)+hyperthermic intraoperative peritoneal chemotherapy (HIPEC) improves survival and/or quality of life compared with standard of care (SoC) in people with peritoneal metastases who
Brian R Davidson, Tim Mould, Kurinchi Gurusamy, Muntzer Mughal, Claire L Vale, R Bhanot, Mark Saunders, Omer Aziz, Sarah O'Dwyer   +8 more
doaj   +1 more source

Effectiveness of the implementation of a perinatal bereavement care training programme on nurses and midwives: protocol for a mixed-method study

BMJ Open, 2022
Introduction The psychological outcomes for many parents who experience perinatal loss depend on nursing staff’s ability to provide effective bereavement support.
Lu Liu, Man Wang, Jialu Qian, Shiwen Sun, Xiaoyan Yu   +4 more
doaj   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Propensity Score-Based Approaches to Confounding by Indication in Individual Patient Data Meta-Analysis: Non-Standardized Treatment for Multidrug Resistant Tuberculosis. [PDF]

PLoS ONE, 2016
BACKGROUND:In the absence of randomized clinical trials, meta-analysis of individual patient data (IPD) from observational studies may provide the most accurate effect estimates for an intervention. However, confounding by indication remains an important
Gregory J Fox, Andrea Benedetti, Carole D Mitnick, Madhukar Pai, Dick Menzies, Collaborative Group for Meta-Analysis of Individual Patient Data in MDR-TB   +5 more
doaj   +1 more source