Results 31 to 40 of about 1,647,935 (248)

Biologics and oral systemic treatment preferences in patients and physicians for moderate-to-severe atopic dermatitis: a discrete choice experiment in the United Kingdom and Germany

Journal of Dermatological Treatment
Background: As the available treatments for moderate-to-severe atopic dermatitis (AD) expand, understanding patient and physician preferences becomes crucial for informed decision-making.Objective: To quantify patient and physician preferences for ...
Nicholas Durno, Pablo Arija, Krystallia Pantiri, Marieke Heisen, Marco Boeri, Josef Paris, Katrin Jack, Olivier Chambenoit, Ramkumar Subramanian, Jorge Puelles, Elly Stolk, Ben van Hout, Jonathan I. Silverberg   +12 more
doaj   +1 more source

Cytoreductive surgery (CRS) with hyperthermic intraoperative peritoneal chemotherapy (HIPEC) versus standard of care (SoC) in people with peritoneal metastases from colorectal, ovarian or gastric origin: protocol for a systematic review and individual participant data (IPD) meta-analyses of effectiveness and cost-effectiveness

BMJ Open, 2020
Introduction There is uncertainty about whether cytoreductive surgery (CRS)+hyperthermic intraoperative peritoneal chemotherapy (HIPEC) improves survival and/or quality of life compared with standard of care (SoC) in people with peritoneal metastases who
Brian R Davidson, Tim Mould, Kurinchi Gurusamy, Muntzer Mughal, Claire L Vale, R Bhanot, Mark Saunders, Omer Aziz, Sarah O'Dwyer   +8 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

CSF and blood levels of Neurofilaments, T-Tau, P-Tau, and Abeta-42 in amyotrophic lateral sclerosis: a systematic review and meta-analysis

Journal of Translational Medicine
Recent literature suggests that markers of neuroaxonal damage, such as neurofilaments and tau protein, might serve as potential biomarkers for ALS. We conducted this systematic review and meta-analysis study to compare cerebrospinal fluid (CSF) and blood
Elmira Agah, Helia Mojtabavi, Atefeh Behkar, Arash Heidari, Atra Ajdari, Zoha Shaka, Seyed Vahid Mousavi, Negar Firoozeh, Abbas Tafakhori, Nima Rezaei   +9 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Treatment options for women with heavy menstrual bleeding: a protocol for comprehensive systematic review, network meta-analyses and health economic assessment

BMJ Open
Introduction A quarter of women experience heavy periods in their lifetime, often significantly impairing their well-being, productivity and quality of life.Several treatment options are offered for heavy menstrual bleeding; however, there is limited ...
Rachael M Hunter, Ewelina Rogozinska, Claire L Vale, Khalid Saeed Khan, David J Fisher, Bassel H Al Wattar, Davor Jurkovic, Ngawai Moss, Jayne F Tierney, Ekaterina Bordea, Niccola Hutchinson-Pascal, Lily Nicholson   +11 more
doaj   +1 more source

Estimation of novel coronavirus (COVID‐19) reproduction number and case fatality rate: A systematic review and meta‐analysis

Health Science Reports, 2021
Background and aims Realizing the transmission potential and the magnitude of the coronavirus disease 2019 (COVID‐19) aids public health monitoring, strategies, and preparation.
Tanvir Ahammed, Aniqua Anjum, Mohammad Meshbahur Rahman, Najmul Haider, Richard Kock, Md Jamal Uddin   +5 more
doaj   +1 more source

The Effect of Corticosteroids on Post-Covid-19 Smell Loss: A Meta-Analysis. [PDF]

, 2023
Mona Kabiri, Maryam Emadzadeh
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Effectiveness of the implementation of a perinatal bereavement care training programme on nurses and midwives: protocol for a mixed-method study

BMJ Open, 2022
Introduction The psychological outcomes for many parents who experience perinatal loss depend on nursing staff’s ability to provide effective bereavement support.
Lu Liu, Man Wang, Jialu Qian, Shiwen Sun, Xiaoyan Yu   +4 more
doaj   +1 more source