Results 41 to 50 of about 1,507,834 (286)

Genetic Profile and Symptom Pattern Explain Variability of Deep Brain Stimulation Effect in Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Bilateral globus pallidus pars interna deep brain stimulation (GPi‐DBS) is a recognized and effective treatment option for drug‐resistant dystonia patients. However, the clinical GPi‐DBS outcomes vary significantly. Herein, we explored the pre‐implant factors affecting GPi‐DBS effectiveness.
Mahboubeh Ahmadipour   +6 more
wiley   +1 more source

Estimation of novel coronavirus (COVID‐19) reproduction number and case fatality rate: A systematic review and meta‐analysis

open access: yesHealth Science Reports, 2021
Background and aims Realizing the transmission potential and the magnitude of the coronavirus disease 2019 (COVID‐19) aids public health monitoring, strategies, and preparation.
Tanvir Ahammed   +5 more
doaj   +1 more source

Meta-analysis of SUMO1 [PDF]

open access: yesBMC Research Notes, 2008
An abundantly growing body of literature implicates conjugation of SUMO in the regulation of many proteins and processes, yet the regulation of SUMO pathways is poorly understood. To gain insight into the players in the SUMO1 pathway I have performed an in-silico co-expression meta-analysis of SUMO1, comparing many different multi-microarray studies of
openaire   +4 more sources

Cervical Spinal Cord Magnetization Transfer Ratio and Its Relationship With Clinical Outcomes in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The cervical spinal cord (cSC) is highly relevant to clinical dysfunction in multiple sclerosis (MS) but remains understudied using quantitative magnetic resonance imaging (MRI). We assessed magnetization transfer ratio (MTR), a semi‐quantitative MRI measure sensitive to MS‐related tissue microstructural changes, in the cSC and its ...
Lisa Eunyoung Lee   +26 more
wiley   +1 more source

Glial Fibrillary Acidic Protein Astrocytopathy Based on a Two‐Center Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glial fibrillary acidic protein astrocytopathy (GFAP‐A) is a recently defined nosological form belonging to the class of autoimmune inflammatory disorders affecting the central nervous system (CNS). Here, we report the clinical and MRI characteristics, treatment, and prognosis of a GFAP‐A cohort from two centers in China.
Ti Wu   +13 more
wiley   +1 more source

Corticosteroids and the Pharmacological Management of Autism—An Integrative Review

open access: yesScientia Pharmaceutica
Autism spectrum disorder (ASD), or autism, is a lifelong neurodevelopmental condition typically detected during early childhood, for which no specific and efficient pharmacological management is currently available.
Lillian Amanda Gabarrão de Jesus   +3 more
doaj   +1 more source

The Comparative Effectiveness and Tolerability of Sphingosine‐1‐Phosphate Receptor Modulators in Patients With Multiple Sclerosis: A Network Meta‐Analysis of Randomized Controlled Trials

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Sphingosine‐1‐phosphate receptor modulators (S1PRM) are used to treat relapsing multiple sclerosis (MS). Each drug has a different S1PR‐subtype selectivity. They target the G‐protein coupled S1P receptors and exert significant immunomodulatory effects, such as preventing the formation of new CNS lesions and the reactivation of pre ...
Faizan Shahzad   +8 more
wiley   +1 more source

Combination of Ledipasvir and Sofosbuvir for Treatment of Hepatitis C Virus Genotype 1 Infection: Systematic Review and Meta-Analysis

open access: yesAnnals of Hepatology, 2017
Background and aim. The combination of Sofosbuvir (SOF) and Ledipasvir (LDV) has been lead to considerable enhancement of treatment of hepatitis C virus (HCV) genotype 1 infection.
Mohammad Saeid Rezaee-Zavareh   +5 more
doaj  

Association Between Atrial Fibrillation and Dementia: A Meta-Analysis

open access: yesFrontiers in Aging Neuroscience, 2019
Background: A potential evidence from previous epidemiological studies remains conflicting findings regarding the association between atrial fibrillation (AF) and dementia risk.
Md. Mohaimenul Islam   +20 more
doaj   +1 more source

A meta‐analysis of humanitarian logistics research [PDF]

open access: yesJournal of Humanitarian Logistics and Supply Chain Management, 2012
Purpose – – The purpose of this paper is to give an up‐to‐date and structured insight into the most recent literature on humanitarian logistics, and suggest trends for future research based on the gaps identified through structured content analysis ...
Nathan Kunz, Gerald Reiner
doaj   +1 more source

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