Results 211 to 220 of about 239,752 (297)

Genetic Regulation of Alternative Polyadenylation Provides Novel Insights into Molecular Mechanisms Underlying Non‐small Cell Lung Cancer

Advanced Science, EarlyView.
Compared with the non‐risk G allele of rs9606, the risk T allele of rs9606 decreases the binding affinity of NUDT21 for LYRM4, triggering 3'UTR shortening that stabilizes LYRM4 mRNA and elevates its expression. Increased LYRM4 expression promoted malignant phenotypes of non‐small cell lung cancer (NSCLC) cells through modulating ferroptosis, supporting
Meng Jin, Yongbiao Huang, Bin Li, Yuan Wang, Yan Li, Zhirui Chen, Zhe Tang, Chaofan Liu, Lei Zhang, Xianglin Yuan, Jianbo Tian, Bo Liu   +11 more
wiley   +1 more source

Accuracy of Large Language Models for Literature Screening in Thoracic Surgery: Diagnostic Study.

J Med Internet Res
Dai ZY, Wang FQ, Shen C, Ji YL, Li ZY, Wang Y, Pu Q.   +6 more
europepmc   +1 more source

Publications of systematic review and meta-analysis in the indexed anesthesia journals: a 10-year bibliometric analysis. [PDF]

Front Med (Lausanne)
Zou ZY, Huang XJ, Song JR, Yao YT.
europepmc   +1 more source

AI‐Driven Defecation Analysis by Smart Healthcare Toilet: Exploring Biometric Patterns and Eu‐Tenesmus

Advanced Science, EarlyView.
A healthcare toilet system is introduced to passively measure defecation behavior. Real‐time data on stool dropping duration, thickness, and a newly defined “eu‐tenesmus” interval show correlations with stool form and gender differences. Results from 45 defecation events reveal a promising method for comprehensive defecation analysis.
Zhiquan Song, TaeHyung Kwon, Jeung Lee, Daeyoun D. Won, Brian J. Lee, Hyuk Soon Choi, Joseph C. Liao, Walter G. Park, Irene Sonu, Stephan Rogalla, Michael J. Rosen, David L. Hu, Jonathan Kuang Ziyang, Sunny Hei Wong, Bong Hyun Jun, Soh Kim, Seung‐min Park   +16 more
wiley   +1 more source

EFTUD2 Regulates Cortical Morphogenesis via Modulation of Caspase‐3 and Aifm1 Splicing Pathways

Advanced Science, EarlyView.
EFTUD2, a spliceosomal GTPase linked to MFDM, regulates cortical development through apoptotic control. Conditional Eftud2 knockout in murine neural stem cells induces microcephaly and cortical disorganization, while pathogenic variants drive neuronal loss.
Liping Chen, Ying Li, Yan Yu, Mingze Cai, Hao Li, Minghe Huang, Guochao Yang, Jiageng Guo, Huailin Wang, Zhihong Song, Wei Shen, Huihui Jiang, Haitao Wu   +12 more
wiley   +1 more source

Efficacy and safety outcomes of emerging EGFR‑TKIs for patients with non‑small cell lung cancer with EGFR exon 20 insertion mutations: A systematic review and meta‑analysis. [PDF]

Oncol Lett
Xie K, Wang J, Jiang J, Deng Z, Hu Q, Wang D.   +5 more
europepmc   +1 more source

Organocatalytic C─O Bond Cleavage and Asymmetric Transformations via [1,3]‐Sigmatropic Rearrangement

Advanced Science, EarlyView.
A direct asymmetric strategy for fulfilling the functional group transfer by aryl ether cleavage and migration is developed, representing the first Brønsted base‐catalyzed asymmetric [1,3]‐sigmatropic rearrangement reaction. The resulting chiral benzofuran products generated through this strategy exhibit significant 3D‐dimensionality and demonstrate ...
Lei Peng, Yu Chang, Liangchen Yin, Jinbang Zhang, Xuli Feng, Pengfei Wang, Wenling Qin, Hailong Yan   +7 more
wiley   +1 more source

Transfer Learning Empowered Multiple‐Indicator Optimization Design for Terahertz Quasi‐Bound State in the Continuum Biosensors

Advanced Science, EarlyView.
This study proposes a pioneering method leveraging transfer learning to optimize multiple indicators in meta‐biosensor design, achieving the multiple‐indicator comprehensive optimization. By adopting frequency shift as a unified criterion, this study quantifies the contribution ratio of each performance indicator to the biosensor, which facilitates ...
Shengfeng Wang, Bingwei Liu, Xu Wu, Zuanming Jin, Yiming Zhu, Linjie Zhang, Yan Peng   +6 more
wiley   +1 more source

Generalized Phase Tailoring of Arbitrary Orthogonal Polarizations in Meta‐Structure with High‐Order Geometric Symmetry

Advanced Science, EarlyView.
A generalized methodology is proposed for Cm (m ≥ 3) meta‐structures to achieve independent phase control of arbitrary orthogonal polarizations. By integrating orientation tuning with structural tailoring, this approach extends spin‐based designs to polarization‐diverse wavefront engineering, enabling multi‐functional and high‐efficiency meta‐devices ...
Kai Qu, Ke Chen, Qi Hu, Weixu Yang, Junming Zhao, Tian Jiang, Yijun Feng   +6 more
wiley   +1 more source