Results 71 to 80 of about 931,154 (348)

Clinical Outcomes Associated With His-Purkinje System Pacing vs. Biventricular Pacing, in Cardiac Resynchronization Therapy: A Meta-Analysis

Frontiers in Cardiovascular Medicine, 2022
AimsHis-Purkinje system pacing has recently emerged as an alternative to biventricular pacing (BIVP) in cardiac resynchronization therapy (CRT). The aim of this study was to conduct a meta-analysis comparing the clinical outcomes associated with His ...
Yang Gui, Lifang Ye, Liuyang Wu, Haohui Mai, Qiqi Yan, Lihong Wang   +5 more
doaj   +1 more source

Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. [PDF]

, 2011
BACKGROUND: Stroke is the major cause of adult disability. Selective serotonin reuptake inhibitors (SSRIs) have been used for many years to manage depression.
Anne Claxton, Cheng-Fang Hsieh, Gillian E Mead, Graeme J Hankey, Mansur A Kutlubaev, Maree L Hackett, Rebecca Lee   +6 more
core   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

OnabotulinumtoxinA for neurogenic detrusor overactivity and dose differences: a systematic review

International Brazilian Journal of Urology, 2015
Purpose To evaluate the efficacy and safety of onabotulinumtoxinA for patients with neurogenic detrusor overactivity (NDO). Materials and Methods We searched the Cochrane Library, PUBMED, EMBASE, Chinese Bio-medicine database, China Journal Full-text ...
Rui Zhang, Yongteng Xu, Shengping Yang, Hui Liang, Yunxin Zhang, Yali Liu   +5 more
doaj   +1 more source

Studies and research design in medicine

Сеченовский вестник, 2021
Adequate design is an essential condition for conducting a successful study. This review describes the most common types of research design in medicine. We discuss the differences between different types of observational and interventional studies, their
N. M. Bulanov, O. B. Blyuss, D. B. Munblit, N. A. Nekliudov, D. V. Butnaru, K. B. Kodzoeva, M. Yu. Nadinskaya, A. A. Zaikin   +7 more
doaj   +1 more source

Contexts of diffusion: Adoption of research synthesis in Social Work and Women's Studies

, 2014
Texts reveal the subjects of interest in research fields, and the values, beliefs, and practices of researchers. In this study, texts are examined through bibliometric mapping and topic modeling to provide a birds eye view of the social dynamics ...
A. Abbott, A. Asuncion, A. Stirling, D.M. Blei, Evidence-Based Medicine Working Group, I. Chalmers, I. Rafols, I. Rafols, J.T. Klein, J.W. Anastas, L. Toews, L.V. Hedges, M. Herie, M.J. Boxer, V. Batagelj   +14 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Riesgo de sesgo de publicación en intervenciones terapéuticas para la COVID-19

Revista Panamericana de Salud Pública, 2021
This article describes publication bias, its most frequent causes, its characteristics, the regulatory tools to avoid it, and some statistical techniques to analyze it. These techniques are explained and applied to three therapeutic interventions related
Santiago Hasdeu, Fernando Tortosa
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

CALIDAD DE VIDA RELACIONADA CON LA SALUD EN TUBERCULOSIS: REVISIÓN SISTEMÁTICA Y METANÁLISIS

Infectio, 2018
Objective: To perform a metanalysis on the effect of the tuberculosis on the dimensions of the SF-36. Methods: Systematic review and meta-analysis, following the PRISMA guide.
Natalia Giraldo
doaj   +1 more source