Results 171 to 180 of about 2,170,654 (281)

Short‐Term Outcomes of Transanal Total Mesorectal Excision for Rectal Cancer: A Multicenter Propensity Score‐Matched Analysis Comparing Patients With and Without Preoperative Neoadjuvant Therapy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim To evaluate the association between preoperative neoadjuvant therapy and short‐term outcomes of transanal total mesorectal excision for rectal cancer. Methods We retrospectively analyzed patients who underwent transanal total mesorectal excision at 26 Japanese institutions between 2012 and 2019.
Takafumi Shima   +57 more
wiley   +1 more source

Epigenome-wide association study meta-analysis of wellbeing. [PDF]

open access: yesClin Epigenetics
Bartels M   +34 more
europepmc   +1 more source

Association of Prophylactic Abdominal Drain Placement With Short‐Term Postoperative Outcomes After Hepatectomy: A Nationwide Inpatient Database Study in Japan

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Although randomized trials have discouraged routine prophylactic abdominal drainage after uncomplicated hepatectomy, these drains are still widely used in clinical practice. This study evaluated the association between prophylactic abdominal drain placement and short‐term outcomes after hepatic resection using a nationwide inpatient ...
Keita Kouzu   +17 more
wiley   +1 more source

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

open access: yesAdvanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

A Multistrategy AI‐Assisted Consensus Screening Pipeline for Discovery of Candidate p53 Monomer Binders

open access: yesAdvanced Intelligent Discovery, EarlyView.
An ultra‐fast small‐sample AI consensus pipeline combines co‐folding and docking to target structure‐lacking p53 monomers. Its optimal mini‐protein binder shows robust interfacial affinity and promising druggability, supplying unprecedented antitumor p53 templates.
Ningyao Li   +9 more
wiley   +1 more source

Large Language Model‐Based Chatbots in Higher Education

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
The use of large language models (LLMs) in higher education can facilitate personalized learning experiences, advance asynchronized learning, and support instructors, students, and researchers across diverse fields. The development of regulations and guidelines that address ethical and legal issues is essential to ensure safe and responsible adaptation
Defne Yigci   +4 more
wiley   +1 more source

Behaviorally Adaptive and Inclusive Advanced Driver‐Assistance Systems

open access: yesAdvanced Intelligent Systems, EarlyView.
Advanced driver‐assistance systems (ADASs) are mapped as evolving human‐centered, adaptive technologies linking sensing, driver monitoring, AR/HUD interfaces, patents, regulation, and inclusive design. The review identifies gaps in real‐world evidence, diverse‐driver validation, gaze metrics, and governance, outlining a roadmap for safer, behaviorally ...
Jana Skirnewskaja   +2 more
wiley   +1 more source

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