Results 41 to 50 of about 845,088 (265)
Partial Evaluation in Meta Modeling [PDF]
, 2007 Meta modeling is a well-established technique to describe the structure modeling languages. Method engineering environments utilize the technique to provide a flexible environment for defining and adapting modeling environments. We show that basing meta modeling strictly on first-order logic provides not only clean semantics but also the ability to ...
openaire +2 more sources
A Meta-Model for Cooperation Systems [PDF]
, 2013 Today’s enterprise information and cooperation systems are numerous and diverse. Users have problems of information overload, task interruption and media discontinuity. A unification approach of existing systems would be supportive to overcome these issues by reducing the variety and thereby the complexity.
Nils Jeners +2 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Optimization and Experimental Verification of Lower Articulation for Low-Floor Tram Using Meta-Model
Applied SciencesThis study aimed to optimize the lower articulation of low-floor trams using a meta-model technique, followed by an experimental validation. The design variables were identified through structural analyses, and the optimization reduced the weight of the ...
Ji-Won Jin +4 more
doaj +1 more source
A Meta-model for Ontologies with ORM2 [PDF]
, 2007 Development of ontology development tools and ontology-enhanced software applications requires thorough understanding of ontology languages in order to implement them according to their specification. We present a formal specification of the ontologies part of the Web Services Modeling Language WSML documentation as a conceptual model in ORM2.
Christina Tziviskou, C. Maria Keet
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
A META-MODEL FOR LOW-CODE CONFIGURATION AND DEPLOYMENT OF CONTENT-BASED IMAGE RETRIEVAL SYSTEMS
Компютерні системи та інформаційні технологіїThe object of this study is content-based image retrieval (CBIR) systems with configurable architectures, and the subject is the meta-model for low-code configuration and deployment of CBIR systems.
Станіслав ДАНИЛЕНКО +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source