Results 91 to 100 of about 19,861,954 (321)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Meta-research matters: Meta-spin cycles, the blindness of bias, and rebuilding trust

PLoS Biology, 2018
Meta-research is research about research. Meta-research may not be as click-worthy as a meta-pug—a pug dog dressed up in a pug costume—but it is crucial to understanding research.
L. Bero
semanticscholar   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Design and analysis of binaural signal matching with arbitrary microphone arrays and listener head rotations

EURASIP Journal on Audio, Speech, and Music Processing
Binaural reproduction is rapidly becoming a topic of great interest in the research community, especially with the surge of new and popular devices, such as virtual reality headsets, smart glasses, and head-tracked headphones.
Lior Madmoni, Zamir Ben-Hur, Jacob Donley, Vladimir Tourbabin, Boaz Rafaely   +4 more
doaj   +1 more source

Journal Data Sharing Policies and Statistical Reporting Inconsistencies in Psychology

Collabra: Psychology, 2017
In this paper, we present three retrospective observational studies that investigate the relation between data sharing and statistical reporting inconsistencies.
Michèle B. Nuijten, Jeroen Borghuis, Coosje L. S. Veldkamp, Linda Dominguez-Alvarez, Marcel A. L. M. Van Assen, Jelte M. Wicherts   +5 more
doaj   +1 more source

Meta-research: Evaluation and Improvement of Research Methods and Practices

PLoS Biology, 2015
As the scientific enterprise has grown in size and diversity, we need empirical evidence on the research process to test and apply interventions that make it more efficient and its results more reliable. Meta-research is an evolving scientific discipline
J. Ioannidis, D. Fanelli, Debbie Drake Dunne, S. Goodman   +3 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Group Conversations in Noisy Environments (GiN) – Multimedia Recordings for Location-Aware Speech Enhancement

IEEE Open Journal of Signal Processing
Recent years have seen a growing interest in the use of smart glasses mounted with microphones to solve the cocktail party problem using beamforming techniques or machine learning.
Emilie d'Olne, Alastair H. Moore, Patrick A. Naylor, Jacob Donley, Vladimir Tourbabin, Thomas Lunner   +5 more
doaj   +1 more source

Research into Educational Management in Portugal: Themes, Focus and Methodologies

Journal of Educational, Cultural and Psychological Studies, 2015
Today, educational management is an expanding scientific field that has been attracting ever more social and political visibility, and it has been the object of a considerable amount of research. In the Portuguese context, over the past two decades there
Leonor L. Torres, Licínio C. Lima
doaj   +1 more source

Care, Social Practices and Normativity. Inner Struggle versus Panglossian Rule-Following [PDF]

, 2019
Contrary to the popular assumption that linguistically mediated social practices constitute the normativity of action (Kiverstein and Rietveld, 2015; Rietveld, 2008a,b; Rietveld and Kiverstein, 2014), I argue that it is affective care for oneself and ...
Jeuk, Alexander Albert
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