Results 71 to 80 of about 68,267,154 (314)

COVID-19 advocacy bias in the BMJ: meta-research evaluation

open access: yesBMJ Open Quality
Objectives During the COVID-19 pandemic, BMJ, a leading journal on evidence-based medicine worldwide, published many views by advocates of specific COVID-19 policies.
John P A Ioannidis   +3 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Informe final de prácticas empresariales Alcaldía Municipal de Guamal-Meta

open access: yes, 2021
Aplicar y complementar los conocimientos adquiridos durante el proceso de formación académica establecida por la Corporación Universitaria del Meta en el programa de Ingeniería Civil, demostrando mis capacidades y destrezas en las actividades diarias ...
Ortega Velasco, Henderson Stiven
core  

ANALISIS PENGENDALIAN KUALITAS PRODUK SARUNG TANGAN GOLF DENGAN METODE SIX SIGMA DALAM UPAYA MENGURANGI KECACATAN PRODUK (Studi Kasus di PT. Adi Satria Abadi, Yogyakarta) [PDF]

open access: yes, 2020
PT Adi Satria Abadi adalah perusahaan yang memproduksi sarung tangan salah satunya adalah sarung tangan golf untuk tujuan ekspor. Dalam proses produksi masih terdapat banyak produk cacat. Oleh karena itu, perlu adanya upaya peningkatan perbaikan kualitas.
Putri, Hana Silvia Dwi   +1 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Neural étendue expander for ultra-wide-angle high-fidelity holographic display

open access: yesNature Communications
Holographic displays can generate light fields by dynamically modulating the wavefront of a coherent beam of light using a spatial light modulator, promising rich virtual and augmented reality applications.
Ethan Tseng   +10 more
doaj   +1 more source

COVID-19 research risks ignoring important host genes due to pre-established research patterns

open access: yeseLife, 2020
It is known that research into human genes is heavily skewed towards genes that have been widely studied for decades, including many genes that were being studied before the productive phase of the Human Genome Project.
Thomas Stoeger, Luís A Nunes Amaral
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Large-scale language analysis of peer review reports

open access: yeseLife, 2020
Peer review is often criticized for being flawed, subjective and biased, but research into peer review has been hindered by a lack of access to peer review reports.
Ivan Buljan   +4 more
doaj   +1 more source

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