Results 51 to 60 of about 1,240,890 (301)

Transparency of COVID-19-related research: A meta-research study

open access: yesPLOS ONE, 2023
Background We aimed to assess the adherence to five transparency practices (data availability, code availability, protocol registration and conflicts of interest (COI), and funding disclosures) from open access Coronavirus disease 2019 (COVID-19) related articles. Methods We searched and exported all open access COVID-19-related articles from PubMed-
Sofi-Mahmudi, Ahmad   +2 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Deformation Driven Suction Cups: A Mechanics‐Based Approach to Wearable Electronics

open access: yesAdvanced Science
Wearable electronics are essential for health monitoring, haptic feedback, and human‐computer interaction. However, maintaining stable contact with skin remains challenging due to its softness, roughness, and variability across body sites.
Seola Lee   +10 more
doaj   +1 more source

Exercise and cancer-related fatigue in adults: a systematic review of previous systematic reviews with meta-analyses

open access: yesBMC Cancer, 2017
Background Conduct a systematic review of previous systematic reviews with meta-analysis to determine the effects of exercise (aerobic, strength or both) on cancer-related-fatigue (CRF) in adults with any type of cancer.
George A. Kelley, Kristi S. Kelley
doaj   +1 more source

Discrepancy review: a feasibility study of a novel peer review intervention to reduce undisclosed discrepancies between registrations and publications

open access: yesRoyal Society Open Science, 2022
Undisclosed discrepancies often exist between study registrations and their associated publications. Discrepancies can increase risk of bias, and when undisclosed, they disguise this increased risk of bias from readers. To remedy this issue, we developed
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Meta-research on Peer Review

open access: yes, 2023
Peer review is a quality control mechanism in scholarly research. Most usage refers to a process in which after a paper has been submitted to a journal - an editor of that journal invites independent (external) experts to evaluate that work and provide advice on how the paper could be improved before it is published and shared with the world.
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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