Results 41 to 50 of about 1,270,902 (311)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
BMC Infectious Diseases, 2018 Background Temporal relationships between the time to appropriate antibiotic therapy and outcomes are not well described. Methods A systematic literature review and meta-analysis was performed to examine this relationship in patients hospitalized with ...
Thomas P. Lodise +4 more
doaj +1 more source
Meta-Research: Broadening the Scope of PLOS Biology
PLOS Biology, 2016 In growing recognition of the importance of how scientific research is designed, performed, communicated, and evaluated, PLOS Biology announces a broadening of its scope to cover meta-research articles.
Stavroula Kousta +2 more
openaire +4 more sources
Unifying Classification Schemes for Software Engineering Meta-Research
CoRR, 2022 This registered report received a In-Principal Acceptance (IPA) in the ESEM 2022 RR track. ESEM 2022: ACM/IEEE International Symposium on Empirical Software Engineering and Measurement - Registered Reports, September 19-23, 2022 Helsinki ...
Angelika Kaplan +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Deformation Driven Suction Cups: A Mechanics‐Based Approach to Wearable Electronics
Advanced ScienceWearable electronics are essential for health monitoring, haptic feedback, and human‐computer interaction. However, maintaining stable contact with skin remains challenging due to its softness, roughness, and variability across body sites.
Seola Lee +10 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
BMC Cancer, 2017 Background Conduct a systematic review of previous systematic reviews with meta-analysis to determine the effects of exercise (aerobic, strength or both) on cancer-related-fatigue (CRF) in adults with any type of cancer.
George A. Kelley, Kristi S. Kelley
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Royal Society Open Science, 2022 Undisclosed discrepancies often exist between study registrations and their associated publications. Discrepancies can increase risk of bias, and when undisclosed, they disguise this increased risk of bias from readers. To remedy this issue, we developed
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source