Results 31 to 40 of about 21,714,712 (299)

Systematic reviews are rarely used to contextualise new results—a systematic review and meta-analysis of meta-research studies

Systematic Reviews, 2022
Background Results of new studies should be interpreted in the context of what is already known to compare results and build the state of the science. This systematic review and meta-analysis aimed to identify and synthesise results from meta-research ...
E. Draborg, J. Andreasen, B. Nørgaard, C. Juhl, J. Yost, K. Brunnhuber, K. Robinson, H. Lund   +7 more
semanticscholar   +1 more source

COVID-19-related medical research: a meta-research and critical appraisal

BMC Medical Research Methodology, 2021
Background Since the start of the COVID-19 outbreak, a large number of COVID-19-related papers have been published. However, concerns about the risk of expedited science have been raised.
M. Raynaud, Huanxi Zhang, Kevin Louis, V. Goutaudier, Jiali Wang, Quentin Dubourg, Yongcheng Wei, Z. Demir, Charlotte Debiais, O. Aubert, Y. Bouatou, C. Lefaucheur, P. Jabre, Longshan Liu, Changxi Wang, X. Jouven, P. Reese, J. Empana, A. Loupy   +18 more
semanticscholar   +1 more source

Mapping and systematic appraisal of umbrella reviews in epidemiological research: a protocol for a meta-epidemiological study

Systematic Reviews, 2023
Introduction Umbrella review is one of the terms used to describe an overview of systematic reviews. During the last years, a rapid increase in the number of umbrella reviews on epidemiological studies has been observed, but there is no systematic ...
Lazaros Belbasis, Robin D Brooker, Emmanuel Zavalis, Angelo Maria Pezzullo, Cathrine Axfors, John PA Ioannidis   +5 more
doaj   +1 more source

Conducting umbrella reviews

BMJ Medicine, 2022
In this article, Lazaros Belbasis and colleagues explain the rationale for umbrella reviews and the key steps involved in conducting an umbrella review, using a working example.
John P A Ioannidis, Vanesa Bellou, Lazaros Belbasis   +2 more
doaj   +1 more source

Treatment effects in randomised trials using routinely collected data for outcome assessment versus traditional trials: meta-research study

British medical journal, 2021
Objective To compare effect estimates of randomised clinical trials that use routinely collected data (RCD-RCT) for outcome ascertainment with traditional trials not using routinely collected data. Design Meta-research study. Data source Studies included
K. M. Mc Cord, Hannah Ewald, A. Agarwal, Dominik Glinz, S. Aghlmandi, J. Ioannidis, L. Hemkens   +6 more
semanticscholar   +1 more source

Justification of research using systematic reviews continues to be inconsistent in clinical health science—A systematic review and meta-analysis of meta-research studies

PLoS ONE, 2022
Background Redundancy is an unethical, unscientific, and costly challenge in clinical health research. There is a high risk of redundancy when existing evidence is not used to justify the research question when a new study is initiated.
J. Andreasen, B. Nørgaard, E. Draborg, C. Juhl, J. Yost, K. Brunnhuber, K. Robinson, H. Lund   +7 more
semanticscholar   +1 more source

Circulating brain-derived neurotrophic factor as a potential biomarker in stroke: a systematic review and meta-analysis

Journal of Translational Medicine, 2022
Background Stroke, an acute cerebrovascular event, is a leading cause of disability, placing a significant psycho-socioeconomic burden worldwide. The adaptation and reorganization process following any neuronal damage is regarded as neuroplasticity ...
Helia Mojtabavi, Zoha Shaka, Sara Momtazmanesh, Atra Ajdari, Nima Rezaei   +4 more
doaj   +1 more source

UKRN Position on Meta-Research

, 2021
UKRN position statement on meta-research. Written by the UKRN Steering Group. This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License (CC BY-SA).
UK Reproducibility Network, UKRN Steering Group   +1 more
openaire   +3 more sources

Assessing the quality of studies in meta‐research: Review/guidelines on the most important quality assessment tools

Pharmaceutical statistics, 2020
Systematic reviews and meta‐analyses pool data from individual studies to generate a higher level of evidence to be evaluated by guidelines. These reviews ultimately guide clinicians and stakeholders in health‐related decisions.
C. Luchini, N. Veronese, A. Nottegar, J. Shin, Giovanni Gentile, Umberto Granziol, P. Soysal, Ovidiu Alexinschi, Lee Smith, M. Solmi   +9 more
semanticscholar   +1 more source

Training early career researchers to use meta-research to improve science: A participant-guided “learn by doing” approach

PLoS Biology, 2021
Meta-research, or the science of science, is a powerful technique that scientists can use to improve science, however most scientists are unaware that meta-research exists and courses are rare.
T. Weissgerber
semanticscholar   +1 more source