Results 91 to 100 of about 21,714,712 (299)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Climate change and health in South Asia: A systematic mapping
The Journal of Climate Change and HealthIntroduction: Climate change is a major threat to human health in South Asia. We mapped existing research on climate change and health in South Asia, identified research gaps, and developed a list of research questions (RQs) to inform a research priority
Inika Sharma +7 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Appraisal of umbrella reviews on vaccines
Communications MedicineUmbrella reviews are systematic reviews of all systematic reviews on a given question and can provide a higher-level view of current available evidence on broad research topics.
Rosa Katia Bellomo, John P. A. Ioannidis
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
IEEE Open Journal of Signal ProcessingRecent years have seen a growing interest in the use of smart glasses mounted with microphones to solve the cocktail party problem using beamforming techniques or machine learning.
Emilie d'Olne +5 more
doaj +1 more source
Journal Data Sharing Policies and Statistical Reporting Inconsistencies in Psychology
Collabra: Psychology, 2017 In this paper, we present three retrospective observational studies that investigate the relation between data sharing and statistical reporting inconsistencies.
Michèle B. Nuijten +5 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Research into Educational Management in Portugal: Themes, Focus and Methodologies
Journal of Educational, Cultural and Psychological Studies, 2015 Today, educational management is an expanding scientific field that has been attracting ever more social and political visibility, and it has been the object of a considerable amount of research. In the Portuguese context, over the past two decades there
Leonor L. Torres, Licínio C. Lima
doaj +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source