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Topography of Generically Folded Spacecapes: Towards a Cognitive Metatheory in Architectural Design [PDF]

open access: yes, 2017
If we visualize philosophy as a science of the sciences (in the tradition of Hans Heinz Holz), then theories within the philosophical framework are always meta-theories of the respective field of interest in question with which philosophy is actually ...
Koutsandrea, Kanelia   +1 more
core   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell   +14 more
wiley   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser   +5 more
wiley   +1 more source

Electrically programmable solid-state metasurfaces via flash localised heating

open access: yesLight: Science & Applications, 2023
A rapid and programmable amplitude modulator based on the thermo-optical effect has been demonstrated by integrating transparent microheaters with metasurfaces.
Khosro Zangeneh Kamali   +7 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Room-temperature optically detected magnetic resonance of single defects in hexagonal boron nitride

open access: yesNature Communications, 2022
Optically active spins in solid-state materials hold promise for future quantum technologies. Here, the authors demonstrate optically detected magnetic resonance at room temperature for single defects in a two-dimensional material, hexagonal boron ...
Hannah L. Stern   +10 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Consciousness and Cosmos: Building an Ontological Framework [PDF]

open access: yes, 2018
Contemporary theories of consciousness are based on widely different concepts of its nature, most or all of which probably embody aspects of the truth about it. Starting with a concept of consciousness indicated by the phrase “the feeling of what happens”
Nixon, Greg   +3 more
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Beliefs about social dynamics and open science

open access: yesRoyal Society Open Science
Open science advocates argue that publicly and freely available scientific manuscripts, data and code will have wide-reaching collective benefits. However, the adoption of open science practices may depend on the fit between researchers' perceptions of ...
Ashley Thomas, Chris Bourg, Rebecca Saxe
doaj   +1 more source

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