Results 51 to 60 of about 617,530 (306)

Immodest and proud [PDF]

open access: yes, 2015
In his ‘Ambitious, Yet Modest, Metaphysics’, Hofweber (Metametaphysics, Oxford University Press, Oxford, pp 260–289, 2009a) puts forward arguments against positions in metaphysics that he describes as ‘immodest’; a position he identifies as defended by ...
B Balcerack-Jackson   +12 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Nonseparability, Classical and Quantum [PDF]

open access: yes, 2010
This paper examines the implications of the holonomy interpretation of classical electromagnetism. As has been argued by Richard Healey and Gordon Belot, classical electromagnetism on this interpretation evinces a form of nonseparability, something that ...
Myrvold, Wayne C.
core  

Wine Tasting Discourse: Traditional Knowledge, and Practice [PDF]

open access: yes, 2016
International audienceTraditions, brotherhoods, wines of terroir, vintage wines…so many expressions that, beyond the numerical value, compose the wine tasting speech, in France as well as in Romania, among others.
Marinescu, Angelica-Helena   +1 more
core   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Beliefs about social dynamics and open science

open access: yesRoyal Society Open Science
Open science advocates argue that publicly and freely available scientific manuscripts, data and code will have wide-reaching collective benefits. However, the adoption of open science practices may depend on the fit between researchers' perceptions of ...
Ashley Thomas, Chris Bourg, Rebecca Saxe
doaj   +1 more source

Room-temperature optically detected magnetic resonance of single defects in hexagonal boron nitride

open access: yesNature Communications, 2022
Optically active spins in solid-state materials hold promise for future quantum technologies. Here, the authors demonstrate optically detected magnetic resonance at room temperature for single defects in a two-dimensional material, hexagonal boron ...
Hannah L. Stern   +10 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Mining the neuroimaging literature

open access: yeseLife
Automated analysis of the biomedical literature (literature mining) offers a rich source of insights. However, such analysis requires collecting a large number of articles and extracting and processing their content.
Jérome Dockès   +4 more
doaj   +1 more source

On Meta-Science

open access: yes, 2015
Here, in this short text, I will try to explore the possibility to define a position that is moving away from science, placing itself outside of it, but at the same time still reflecting it, still remembering science. If it is possible to define such a position, then it would have the properties of meta-science (the way it has been defined in the ...
openaire   +1 more source

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