Results 41 to 50 of about 636,756 (264)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Soft photo-ionotronics

open access: yesNature Communications
The ability to control the movement of charged species in the circuitry of living beings and machines is essential for complex signal processing, computation, and, ultimately, higher functionality. We describe a class of photo-ion generators (PIGs) based
Xu Liu   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Citation Metric Misuse, Interpretive Ambiguity, and Interdisciplinary Complexity—The Case in Biomechanics Journals

open access: yesJournal of Information Science Theory and Practice
Biomechanics is an interdisciplinary field with varying citation patterns and centrality of journals where researchers publish. The audit culture of scientific publication has driven persistent, inconsistent, and questionable interpretation of citations ...
Duane Knudson
doaj   +1 more source

A Perspective on the Relevance and Public Reception of Psychological Science

open access: yesCollabra: Psychology, 2019
In this short commentary, data from the website Reddit is used to examine how people receive social psychological research. The data show that people care greatly about research dealing with humans: links tagged as psychology, social sciences, and health
Jonathon McPhetres
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Improving reproducibility of GIScience publications through novel reproducibility guidelines and revised review procedures

open access: yesJournal of Spatial Information Science
Recent research in the field of geographic information science shows that reproducibility and replicability of publications have substantial room for improvement and proposes various actions to improve the situation.
Carlos Granell   +9 more
doaj   +1 more source

Markers of immune dysregulation in response to the ageing gut: insights from aged murine gut microbiota transplants

open access: yesBMC Gastroenterology, 2022
Background Perturbations in the composition and diversity of the gut microbiota are accompanied by a decline in immune homeostasis during ageing, characterized by chronic low-grade inflammation and enhanced innate immunity.
Panagiotis Giannos   +3 more
doaj   +1 more source

Meta-Science: Towards a Science of Meaning and Complex Solutions

open access: yes, 2023
Science has lost its ethical imperatives as it moved away from a science of ought to a science of is. Subsequently, it might have answers for how we can address global challenges, such as climate change and poverty, but not why we should. This supposedly neutral stance leaves it to politics and religions (in the sense of non-scientific fields of social
openaire   +2 more sources

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