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When a review is performed following predefined steps (ie, systematically) and its results are quantitatively analyzed, it is called meta-analysis. Publication of meta-analyses has increased exponentially in pubmed.gov; using the key word "meta-analysis," 1,473 titles were yielded in 2007 and 176,704 on January 2020.
Adrian V, Hernandez +2 more
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In a meta‐analysis, we assemble a sample of independent, nonidentically distributed p‐values. The Fisher's combination procedure provides a chi‐squared test of whether the p‐values were sampled from the null uniform distribution. After rejecting the null uniform hypothesis, we are faced with the problem of how to combine the assembled p‐values.
Chang Yu, Daniel Zelterman
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Meta-analysis in Otolaryngology [PDF]
To examine the results of meta-analyses in otolaryngology and compare these results with the individual component studies that constitute each meta-analysis.A retrospective review of the literature.Studies that conducted pooled statistical systematic analyses indexed on MEDLINE for the 10-year period from January 1989 to January 1999 were selected for ...
R, Alsarraf +3 more
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Meta‐Analysis, Meta‐Regression, and Meta‐Physics [PDF]
Παντɛςανθρωποιτοv ɛιδɛναιορɛγονταιφvσɛι. σημɛιονδɛητωναισθησɛωναγαπησις. Kαιγαρχωριςτηςχρɛιαςαγαπωνταιδι' αvτας, καιμαλλιστατωναλλωνηδιατωνομματων. By nature humans thirst for knowledge. A sign of this is our love of the senses. Because irrespective of our needs we love our senses in themselves and most of all vision (eyesight).1
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Meta-analysis is the quantitative synthesis of information from several studies. It is applicable to a variety of study designs in genetics, from family-based linkage studies and population-based association studies to genome-wide scans and genome-wide association studies. By combining relevant evidence from many studies, statistical power is increased
Trikalinos, T. A. +3 more
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An abundantly growing body of literature implicates conjugation of SUMO in the regulation of many proteins and processes, yet the regulation of SUMO pathways is poorly understood. To gain insight into the players in the SUMO1 pathway I have performed an in-silico co-expression meta-analysis of SUMO1, comparing many different multi-microarray studies of
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Meta-analysis is the science of combining evidence from different studies, but traditional statistical techniques contain neither a formal definition nor a measure of evidence. It is argued in this paper that the log-likelihood ratio, as a measure of the "weight of evidence," can be a very useful tool in the meta-analysis.
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Exploring heterogeneity in meta-analysis: Meta-regression analysis [PDF]
Loukia M. Spineli, Nikolaos Pandis
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