Results 121 to 130 of about 3,290,125 (315)

Pain reporting and analgesia management in 270 children with a progressive neurologic, metabolic or chromosomally based condition with impairment of the central nervous system: cross-sectional, baseline results from an observational, longitudinal study

Journal of Pain Research, 2017
Stefan J Friedrichsdorf,1,2 Andrea C Postier,1 Gail S Andrews,3 Karen ES Hamre,4 Rose Steele,5 Harold Siden6,7 1Department of Pain Medicine, Palliative Care and Integrative Medicine, Children’s Hospitals and Clinics of Minnesota, MN, USA ...
Friedrichsdorf SJ, Postier AC, Andrews GS, Hamre KES, Steele R, Siden H   +5 more
doaj  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

New Players in Metabolic Syndrome

Background/Objectives: Metabolic syndrome (MetS) is a complex, multifaceted disorder with significant socioeconomic and public health consequences, increasingly acknowledged as a global epidemic.
Vlayko Vodenicharov, Vera Karamfilova, Tsvetelina Velikova, Yavor Assyov, Iveta Nedeva, Zdravko Kamenov, Pavel Dobrev   +6 more
core   +1 more source

A new Korean nomenclature for steatotic liver disease [PDF]

Clinical and Molecular Hepatology
Nonalcoholic Fatty Liver Disease (NAFLD) Nomenclature Revision Consensus Task Force on behalf of the Korean Association for the Study of the Liver (KASL)
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Metabolic Outcomes in Bariatric/Metabolic Surgery Individuals: Impact of Metabolic Health Definition, Type of Surgery, and Follow-Up Duration—An Observational, Retrospective Study

Background: There is no standardized definition for metabolic health. Overweight and obesity are often linked to metabolic dysfunction. Bariatric surgery promotes body weight loss and cardiometabolic health improvement.
Maria João Martins, Eduardo Lima, Denise Pinheiro, Alexandra Leitão, Pluemacher, Anna, Freitas, Paula, Bárbara Peleteiro, Pinheiro, Denise, Martins, Maria Jo\ue3o, Dias, Cl\ue1udia Camila, Peleteiro, B\ue1rbara, Martins, Elisabete, Leit\ue3o, Alexandra, Paula Freitas, Lima, Eduardo, Anna Pluemacher, Cláudia Camila Dias, Elisabete Martins   +17 more
core   +1 more source

The impact of obesity and inflammation on metabolic risk factors for cardiovascular disease and type two diabetes in black and white South African women [PDF]

, 2011
[T]he overall aim of this thesis was to investigate the ethnic-specific role of inflammation in obesity and related metabolic risk factors associated with T2DM and CVD in apparently healthy black and white premenopausal South African ...
Evans, Juliet P
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Hypertension in the Metabolic Syndrome

, 2005
In the history of the Metabolic Syndrome hypertension has played a major role because it is the element that has transformed the well known metabolic cluster of obesity dyslipidemia and diabetes into a true syndrome (the sum of apparently different ...
Natali A., Ferrannini E.
core   +1 more source

Investigating Müller glia reprogramming in mice: a retrospective of the last decade, and a look to the future

Neural Regeneration Research
Müller glia, as prominent glial cells within the retina, plays a significant role in maintaining retinal homeostasis in both healthy and diseased states.
Zhiyuan Yin, Jiahui Kang, Xuan Cheng, Hui Gao, Shujia Huo, Haiwei Xu   +5 more
doaj   +1 more source