Results 31 to 40 of about 3,290,125 (315)

Study of respiratory chain dysfunction in heart disease [PDF]

Journal of Cardiovascular and Thoracic Research, 2018
The relentlessly beating heart has the greatest oxygen consumption of any organ in the body at rest reflecting its huge metabolic turnover and energetic demands.
Seyyed Hossein Hassanpour, Mohammad Amin Dehghani, Seyyedeh Zeinab Karami   +2 more
doaj   +1 more source

ALG1-CDG Caused by Non-functional Alternative Splicing Involving a Novel Pathogenic Complex Allele

Frontiers in Genetics, 2021
This study reports on a Mexican mestizo patient with a multi-systemic syndrome including neurological involvement and a type I serum transferrin profile.
Carlos Alberto González-Domínguez, Carlos Alberto González-Domínguez, Moisés O. Fiesco-Roa, Moisés O. Fiesco-Roa, Samuel Gómez-Carmona, Anke Paula Ingrid Kleinert-Altamirano, Anke Paula Ingrid Kleinert-Altamirano, Miao He, Earnest James Paul Daniel, Kimiyo M. Raymond, Melania Abreu-González, Sandra Manrique-Hernández, Sandra Manrique-Hernández, Ana González-Jaimes, Roberta Salinas-Marín, Carolina Molina-Garay, Karol Carrillo-Sánchez, Luis Leonardo Flores-Lagunes, Marco Jiménez-Olivares, Anallely Muñoz-Rivas, Mario E. Cruz-Muñoz, Matilde Ruíz-García, Hudson H. Freeze, Héctor M. Mora-Montes, Carmen Alaez-Verson, Iván Martínez-Duncker, Iván Martínez-Duncker   +26 more
doaj   +1 more source

Gender, socio-economic status and metabolic syndrome in middle-aged and old adults. [PDF]

, 2008
BACKGROUND: Studies that addressed social and economic determinants of cardiovascular diseases, consistently showed an increase prevalence of the individual features of metabolic syndrome in the lower socio-economic strata.
Barros, Henrique, Henrique Barros, Santos, Ana C, Ana C Santos, Shah Ebrahim, Ebrahim, Shah, Santos Ana C, Barros Henrique, Ebrahim Shah   +8 more
core   +2 more sources

Preprint: Using genetics to uncouple higher adiposity from its adverse metabolic effects and understand its role in metabolic and non-metabolic disease

, 2021
To understand the consequences of higher adiposity uncoupled from its adverse metabolic effects, we selected 37 diseases associated with obesity and genetic variants associated with different aspects of excess weight including metabolically “favourable ...
Lam Tsoi, Christopher Kabrhel, Philip E Stuart, Marc Gunter, Emma Vincent, Robin Beaumont, Philip Law, Caroline Bull, Hanieh Yaghootkar, Elizabeth Thomas, Timothy Frayling, Nikos Papadimitriou, Joshua Bell, Naveed Sattar, Jessica Tyrrell, Andrew Wood, Richard Houlston, Susan Martin, Jimmy Bell, Matthew Bown, James Elder   +20 more
core   +1 more source

The Interplay between Immune and Metabolic Pathways in Kidney Disease

Cells, 2023
Kidney disease is a significant health problem worldwide, affecting an estimated 10% of the global population. Kidney disease encompasses a diverse group of disorders that vary in their underlying pathophysiology, clinical presentation, and outcomes ...
Lili Qu, Baihai Jiao
doaj   +1 more source

Identification of a Four-Gene Metabolic Signature to Evaluate the Prognosis of Colon Adenocarcinoma Patients

Frontiers in Public Health, 2022
BackgroundColon adenocarcinoma (COAD) is a highly heterogeneous disease, thus making prognostic predictions uniquely challenging. Metabolic reprogramming is emerging as a novel cancer hallmark that may serve as the basis for more effective prognosis ...
Yang Zheng, Yang Zheng, Rilige Wu, Ximo Wang, Ximo Wang, Ximo Wang, Chengliang Yin   +6 more
doaj   +1 more source

The metabolic effect of combined liraglutide treatment and lifestyle modification on obese adolescents in a tertiary center, Riyadh

Frontiers in Endocrinology
BackgroundObesity has increased in adolescents with a rising incidence of metabolic consequences, including type 2 diabetes, necessitating new pharmacotherapeutic approaches.
Amir Babiker, Amir Babiker, Amir Babiker, Haifa Alfaraidi, Haifa Alfaraidi, Haifa Alfaraidi, Gadah Aljarallah, Joud Albaraki, Reem Alharbi, Nouf Alsomali, Abeer Alkhalaf, Nagarajkumar Yenugadhati, Nagarajkumar Yenugadhati, Fahad Al Juraibah, Fahad Al Juraibah, Fahad Al Juraibah, Ibrahim Al Alwan, Ibrahim Al Alwan, Ibrahim Al Alwan   +18 more
doaj   +1 more source

Clinical Implication of Sarcopenia in Patients with Inflammatory Bowel Disease

The Korean Journal of Gastroenterology, 2018
Recent studies have shown that inflammatory bowel disease (IBD) patients are affected by altered body composition, especially low muscle mass or sarcopenia.
Seong-Eun Kim
doaj   +1 more source

Metabolic Profiling and Transcriptome Analysis Reveal the Key Role of Flavonoids in Internode Coloration of Phyllostachys violascens cv. Viridisulcata

Frontiers in Plant Science, 2022
Bamboo, being an ornamental plant, has myriad aesthetic and economic significance. Particularly, Phyllostachys violascens cv. Viridisulcata contains an internode color phenotype in variation in green and yellow color between the sulcus and culm ...
Han-tian Wei, Dan Hou, Muhammad Furqan Ashraf, Hai-Wen Lu, Juan Zhuo, Jia-long Pei, Qi-xia Qian   +6 more
doaj   +1 more source

Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg effect [PDF]

, 2011
The Warburg effect - a classical hallmark of cancer metabolism - is a counter-intuitive phenomenon in which rapidly proliferating cancer cells resort to inefficient ATP production via glycolysis leading to lactate secretion, instead of relying primarily ...
Tomer Shlomi, Eyal Gottlieb, Gottlieb, E., Shlomi, T., Gottlieb Eyal, Roded Sharan, Eytan Ruppin, Ruppin Eytan, Tomer Benyamini, Shlomi Tomer, Sharan Roded, Benyamini Tomer, Ruppin, E., Benyamini, T., Sharan, R.   +14 more
core   +1 more source