Results 61 to 70 of about 5,522,237 (352)

Multidimensional difference analysis in gastric cancer patients between high and low latitude

Frontiers in Genetics, 2022
Genetic variation has been shown to affect tumor growth and progression, and the temperature at different latitudes may promote the evolution of genetic variation.
Liqiang Wang, Liqiang Wang, Mengdi Cai, Mengdi Cai, Ying Song, Ying Song, Jing Bai, Jing Bai, Wenjing Sun, Wenjing Sun, Jingcui Yu, Jingcui Yu, Shuomeng Du, Shuomeng Du, Jianping Lu, Songbin Fu, Songbin Fu   +16 more
doaj   +1 more source

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.

Cell, 2006
Diminished mitochondrial oxidative phosphorylation and aerobic capacity are associated with reduced longevity. We tested whether resveratrol (RSV), which is known to extend lifespan, impacts mitochondrial function and metabolic homeostasis.
Marie Lagouge, Carmen A. Argmann, Zachary Gerhart-Hines, H. Meziane, C. Lerin, F. Daussin, N. Messadeq, J. Milne, P. Lambert, P. Elliott, B. Gény, M. Laakso, P. Puigserver, J. Auwerx   +13 more
semanticscholar   +1 more source

Metabolic reprogramming and cancer progression

Science, 2020
Metabolism as cancer progresses Numerous cancer-specific alterations in metabolism have been identified but have not yet resulted in an effective anti cancer therapeutic. In a Review, Faubert et al.
B. Faubert, Ashley Solmonson, R. Deberardinis   +2 more
semanticscholar   +1 more source

Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction [PDF]

, 2011
BACKGROUND: Burkholderia cenocepacia is a threatening nosocomial epidemic pathogen in patients with cystic fibrosis (CF) or a compromised immune system. Its high level of antibiotic resistance is an increasing concern in treatments against its infection.
Fang, K., Zhao, H., Changyue Sun, Lam, M.C., Chang, S., Zhang, K., Panda, G., Godinho, M., Martins Dos Santos, V.A.P., Wang, J.   +9 more
core   +2 more sources

Quantifying biosynthetic network robustness across the human oral microbiome [PDF]

, 2018
Metabolic interactions, such as cross-feeding, play a prominent role in microbial communitystructure. For example, they may underlie the ubiquity of uncultivated microorganisms.
Bernstein, David, Dewhirst, Floyd, Segre, Daniel   +2 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Myositis mimics

Indian Journal of Rheumatology, 2021
Proximal muscle weakness in children, as well as adults, can be the presenting feature of a wide range of diseases including but not limited to the idiopathic inflammatory myopathies, muscle dystrophies, metabolic, endocrine, and drug-induced myopathies.
Sujata Ganguly, Rudrarpan Chatterjee, Abhishek Zanwar, Latika Gupta   +3 more
doaj   +1 more source

Impact of Noise Exposure on Risk of Developing Stress-Related Obstetric Health Effects: A Systematic Review and Meta-Analysis

Noise and Health, 2022
Background: Exposure to noise can increase biological stress reactions and that could increase the risk of stress-related prenatal effects, including adverse obstetric outcomes; however, the association between exposure to noise and adverse obstetric ...
Kapeena Sivakumaran, Jennifer A Ritonja, Haya Waseem, Leena AlShenaibar, Elissa Morgan, Salman A Ahmadi, Allison Denning, David Michaud, Rebecca L Morgan   +8 more
doaj   +1 more source

The metabolic syndrome in type 2 diabetic subjects in Gorgan, Iran [PDF]

, 2011
Objective: To assess the prevalence of the metabolic syndrome in subjects diagnosed with Type 2 diabetes in Gorgan, Iran.Methods: Data were collected from 200 subjects with Type 2 diabetes mellitus and they were categorized aswith or without the ...
Marjani, A., Mojerloo, M.
core  

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source