Results 101 to 110 of about 79,003 (287)

Association between early metabolic acidosis and bronchopulmonary dysplasia/death in preterm infants born at less than 28 weeks’ gestation: an observational cohort study

BMC Pediatrics
Background Metabolic acidosis occurs frequently during the first postnatal days in extremely preterm infants and is mainly attributed to renal immaturity. Recent studies suggested a link between metabolic acidosis and the development of BPD.
Laura Notz, Mark Adams, Dirk Bassler, Vinzenz Boos   +3 more
doaj   +1 more source

Effects of metabolic acidosis and starvation on the content of intermediary metabolites in rat kidney [PDF]

, 1971
D.A. Hems, John T. Brosnan
openalex   +1 more source

Vascularized Tumor‐on‐a‐Chip Model as a Platform for Studying Tumor‐Microenvironment‐Drug Interaction

Macromolecular Bioscience, EarlyView.
Vascularized tumor‐on‐a‐chip platforms replicate human tumor microenvironments by integrating perfusable vessels and stromal elements in microfluidic systems. These models enable dynamic assessment of drug delivery and therapeutic response under physiologically relevant flow, offering enhanced predictive value for cancer treatment.
Hyelim Kim, Seung‐Woo Cho, Hong Nam Kim   +2 more
wiley   +1 more source

Significance of Correction of Metabolic Acidosis on the Cardiovascular Dynamics

, 1967
Shoji Eguchi, Hisashi ISOGAWA, Masanori Terashima, Kenichi Asano   +3 more
openalex   +2 more sources

Metabolic acidosis in patients receiving anticonvulsants [PDF]

, 1979
Iwao Matsuda, Bunsaku Nagai, Tatsuya Kondo, Naoyuki Taniguchi, S. Arashima, Takashi Mitsuyama, Yogo Oka, Misato Homma   +7 more
openalex   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Increased Susceptibility of the Heart to Ventricular Fibrillation During Metabolic Acidosis

, 1966
Paul H. Gerst, William H. Fleming, James R. Malm   +2 more
openalex   +1 more source

Unexpected metabolic acidosis during rectal surgery [PDF]

, 1978
J. Hurdley
openalex   +1 more source

The Dual Role of Exosomes in the Tumor Microenvironment: From Pro‐Tumorigenic Signaling to Immune Modulation

Med Research, EarlyView.
Tumor‐derived exosomes influence proliferation, invasion, angiogenesis, metabolic adaptation, and resistance to therapy. They also shape the immune landscape by modulating antigen presentation, suppressing cytotoxic lymphocyte activity, and promoting the expansion of immunosuppressive cell populations. Although frequently associated with immune evasion,
Jiale Li, Jun Peng, Jiachong Wang, Zigui Chen   +3 more
wiley   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen, Chaozhuang Shen, Yuchen Tian, Yuhe Peng, Jing Hu, Haitang Xie, Ping Yin   +6 more
wiley   +1 more source