Results 21 to 30 of about 89,224 (302)

Metabolic Acidosis and Subclinical Metabolic Acidosis in CKD [PDF]

open access: yesJournal of the American Society of Nephrology, 2017
Metabolic acidosis is not uncommon in CKD and is linked with bone demineralization, muscle catabolism, and higher risks of CKD progression and mortality. Clinical practice guidelines recommend maintaining serum total CO2 at ≥22 mEq/L to help prevent these complications.
openaire   +2 more sources

Reversible acute blindness in suspected metformin-associated lactic acidosis: a case report

open access: yesJournal of Medical Case Reports, 2023
Background Metformin is commonly used for the treatment of type 2 diabetes mellitus. Its multiple advantages include low risk of hypoglycemia, weight neutrality, low cost, and cardioprotective and anti-inflammatory effects.
Rui Huang, Wentao Sun
doaj   +1 more source

Pathophysiological aspect of metabolic acid-base disorders [PDF]

open access: yesMedicinski Podmladak, 2016
Maintaing the arterial pH values (in normal range of 7,35-7,45) is one of the main principles of homeostasis. Regulatory responses, including chemical buffering (extracellular, intracellular, sceletal), the regulation of pCO2 by the respiratory system ...
Nešović-Ostojić Jelena
doaj   +1 more source

Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA. [PDF]

open access: yesPLoS Genetics, 2010
Although lactic acidosis is a prominent feature of solid tumors, we still have limited understanding of the mechanisms by which lactic acidosis influences metabolic phenotypes of cancer cells. We compared global transcriptional responses of breast cancer
Julia Ling-Yu Chen   +9 more
doaj   +1 more source

Effect of sodium bicarbonate infusion on hospital mortality in acute kidney injury patients with metabolic acidosis

open access: yesFrontiers in Medicine, 2023
BackgroundPhysicians usually consider that sodium bicarbonate (SB) infusion can be used for metabolic acidosis; however, there is little evidence available to assess its effect on hospital mortality in large AKI cohorts.
Yunting Wang   +6 more
doaj   +1 more source

Prevalence and severity of metabolic acidosis in patients on maintenance hemodialysis in India

open access: yesMedical Journal of Dr. D.Y. Patil University, 2016
Aim: Metabolic acidosis is a feature of chronic kidney disease (CKD) due to the reduced capacity of the kidney to synthesize ammonia and excrete hydrogen ions.
Atul D Sajgure   +7 more
doaj   +1 more source

Metabolic Acidosis in the Alligator.

open access: yesExperimental Biology and Medicine, 1958
SummarySympathomimetic agents produce a severe lactate acidemia in the alligator. Although the lactate concentration often exceeded the initial alkali reserve, over 90% survived by withdrawing sodium from sources outside the extracellular fluid. The extracellular osmotic pressure rose sharply during the acute acidotic phase and fell when the lactate ...
T, HERNANDEZ, R A, COULSON
openaire   +2 more sources

Drug-Induced Metabolic Acidosis [version 1; referees: 3 approved]

open access: yesF1000Research, 2015
Metabolic acidosis could emerge from diseases disrupting acid-base equilibrium or from drugs that induce similar derangements. Occurrences are usually accompanied by comorbid conditions of drug-induced metabolic acidosis, and clinical outcomes may range ...
Amy Quynh Trang Pham   +2 more
doaj   +1 more source

Successful perioperative management of living-donor liver transplantation for a patient with severe methylmalonic acidemia: a case report

open access: yesJA Clinical Reports, 2018
Background Methylmalonic acidemia (MMAemia) is a rare hereditary disease affecting organic acid metabolism. It causes recurrent metabolic acidosis and secondary mitochondrial dysfunction, resulting in a poor prognosis. Liver transplantation (LT) has been
Akiko Hirotsu   +6 more
doaj   +1 more source

High-anion gap hyperchloremic acidosis mimicking diabetic ketoacidosis on initial presentation – Case report

open access: yesAfrican Journal of Emergency Medicine, 2020
Introduction: Diabetic ketoacidosis (DKA) often becomes the primary focus and in turn masks a similar serious condition like hyperchloremic metabolic acidosis.
Esmail Sangey, Kishan Chudasama
doaj   +1 more source

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