Results 21 to 30 of about 1,011,106 (292)

Triggering of erythropoietin production by hypoxia is inhibited by respiratory and metabolic acidosis [PDF]

, 1990
Erythropoietin (EPO) production in response to hypoxic hypoxia is known to be attenuated by simultaneous hypercapnia. This study aimed to investigate whether this inhibitory effect of hypercapnia is 1) a direct effect of carbon dioxide or mediated by ...
Eckardt, K. U., Kurtz, Armin, Bauer, C., A. Kurtz, C. Bauer, K. U. Eckardt   +5 more
core   +1 more source

A rare case report of combined metformin-associated lactic acidosis and diabetic ketoacidosis

The Egyptian Journal of Internal Medicine, 2022
Background Triad of diabetic ketoacidosis (DKA) comprises of hyperglycemia with serum glucose > 11 mmol/L, high anion gap metabolic acidosis and ketonemia. Hyperlactemia is often noted in patients with DKA.
Yudara Kularathne, Shaun Goh, Sohil Pothiawala   +2 more
doaj   +1 more source

Biochemistry of exercise-induced metabolic acidosis [PDF]

, 2004
The development of acidosis during intense exercise has traditionally been explained by the increased production of lactic acid, causing the release of a proton and the formation of the acid salt sodium lactate.
Farzenah Ghiasvand, Robert A. Robergs, Daryl Parker, Parker, Daryl, Robergs, Robert A., Ghiasvand, Farzenah   +5 more
core   +1 more source

Reversible acute blindness in suspected metformin-associated lactic acidosis: a case report

Journal of Medical Case Reports, 2023
Background Metformin is commonly used for the treatment of type 2 diabetes mellitus. Its multiple advantages include low risk of hypoglycemia, weight neutrality, low cost, and cardioprotective and anti-inflammatory effects.
Rui Huang, Wentao Sun
doaj   +1 more source

Metabolic Acidosis and Subclinical Metabolic Acidosis in CKD [PDF]

Journal of the American Society of Nephrology, 2017
Metabolic acidosis is not uncommon in CKD and is linked with bone demineralization, muscle catabolism, and higher risks of CKD progression and mortality. Clinical practice guidelines recommend maintaining serum total CO2 at ≥22 mEq/L to help prevent these complications.
openaire   +2 more sources

Metabolic Acidosis in Patients with Chronic Kidney Disease: Diagnosis, Pathogenesis, and Treatment—A Narrative Review [PDF]

Diagnostics
Tomasz Gołębiowski, Slawomir Zmonarski, Maciej Szymczak   +2 more
exaly   +2 more sources

Metabolic acidosis in critically ill patients with cirrhosis: Epidemiology and short-term mortality risk factors

The Turkish Journal of Gastroenterology, 2019
Background/Aims: Metabolic acidosis is a common complication in patients with cirrhosis at the intensive care units (ICUs) and associated with increased mortality.
Feng Gao, Miao-Tong Lin, Xing-Yi Yang, Meng-Xing Cai, Hao- Nan, Wei Xie, Zhi-Ming Huang   +6 more
doaj   +1 more source

Pathophysiological aspect of metabolic acid-base disorders [PDF]

Medicinski Podmladak, 2016
Maintaing the arterial pH values (in normal range of 7,35-7,45) is one of the main principles of homeostasis. Regulatory responses, including chemical buffering (extracellular, intracellular, sceletal), the regulation of pCO2 by the respiratory system ...
Nešović-Ostojić Jelena
doaj   +1 more source

Effect of sodium bicarbonate infusion on hospital mortality in acute kidney injury patients with metabolic acidosis

Frontiers in Medicine, 2023
BackgroundPhysicians usually consider that sodium bicarbonate (SB) infusion can be used for metabolic acidosis; however, there is little evidence available to assess its effect on hospital mortality in large AKI cohorts.
Yunting Wang, Yunting Wang, Ling Chen, Guangfeng Guo, Youyuan Gao, Youyuan Gao, Hua Gan   +6 more
doaj   +1 more source

Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA. [PDF]

PLoS Genetics, 2010
Although lactic acidosis is a prominent feature of solid tumors, we still have limited understanding of the mechanisms by which lactic acidosis influences metabolic phenotypes of cancer cells. We compared global transcriptional responses of breast cancer
Julia Ling-Yu Chen, Daniel Merl, Christopher W Peterson, Jianli Wu, Patrick Yantyng Liu, Hanwei Yin, Deborah M Muoio, Don E Ayer, Mike West, Jen-Tsan Chi   +9 more
doaj   +1 more source