Results 31 to 40 of about 79,003 (287)
Frontiers in Pharmacology, 2022 Objective: Metabolic acidosis often occurs in the paediatric intensive care unit (PICU). Although sodium bicarbonate (SB) has been widely used in paediatrics, data on the effect of SB on children with metabolic acidosis in the PICU are scarce.Methods ...
Huabin Wang +10 more
doaj +1 more source
Randomized preclinical study of machine perfusion in vascularized composite allografts
BJS (British Journal of Surgery), EarlyView., 2020 This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin +7 more
wiley +1 more source
Etiology and Management of Acute Metabolic Acidosis: An Update
Kidney & Blood Pressure Research, 2020 Background: The etiology of acute metabolic acidosis (aMA) is heterogeneous, and the consequences are potentially life-threatening. The aim of this article was to summarize the causes and management of aMA from a clinician’s perspective.
Igor Matyukhin +3 more
doaj +1 more source
The cause of metabolic acidosis [PDF]
Kidney International, 2010 To the Editor: As a case of ‘make your diagnosis’, Chang et al.1 presented a case with metabolic acidosis. Although the authors attributed the acid–base disorder of the case to D-lactic acidosis, the laboratory findings would indicate that the case had hyperchloremic acidosis in addition to D-lactic acidosis.
openaire +2 more sources
Normal anion gap metabolic acidosis secondary to topiramate intake: case report
Case Reports, 2018 Introduction: Topiramate is a drug used to treat various types of epilepsy and as prophylaxis in cases of migrainous headache. One of its mechanisms of action is the inhibition of carbonic anhydrase in the kidney that triggers the excretion of alkaline ...
Jorge Fernando Miño-Bernal +3 more
doaj +1 more source
Primary assessment of patients admitted to the emergency ward using arterial blood gas
MGM Journal of Medical Sciences, 2022 Background: Arterial blood gas study (ABG) is a point-of-care testing (POCT) diagnostic tool that can furnish metabolic and respiratory aberrations. This study was conducted systematically, to assess the metabolic and respiratory aberrations quickly and ...
Sanjay Mulay +3 more
doaj +1 more source
Sodium Bicarbonate Therapy in Patients with Metabolic Acidosis
The Scientific World Journal, 2014 Metabolic acidosis occurs when a relative accumulation of plasma anions in excess of cations reduces plasma pH. Replacement of sodium bicarbonate to patients with sodium bicarbonate loss due to diarrhea or renal proximal tubular acidosis is useful, but ...
María M. Adeva-Andany +4 more
doaj +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Kidney & Blood Pressure Research, 2018 Metabolic acidosis is commonly found in patients with chronic kidney disease (CKD), and its causes are: impaired ammonia excretion, reduced tubular bicarbonate reabsorption and insufficient renal bicarbonate production in relation to the amount of acids ...
Marcin Adamczak +5 more
doaj +1 more source
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2020 Background Lentiform fork sign is a neuroradiological abnormality which is encountered in the clinical practice associated with uremic encephalopathy, dialysis disequilibrium syndrome and metabolic acidosis.
Salman Mansoor +10 more
doaj +1 more source