Assessment of severe malaria in a multicenter, phase III, RTS, S/AS01 malaria candidate vaccine trial: case definition, standardization of data collection and patient care. [PDF]
, 2011 BACKGROUND\ud \ud An effective malaria vaccine, deployed in conjunction with other malaria interventions, is likely to substantially reduce the malaria burden. Efficacy against severe malaria will be a key driver for decisions on implementation.
Amanda Leach +18 more
core +4 more sources
Primary care physicians' perceptions of barriers and facilitators to management of chronic kidney disease: A mixed methods study. [PDF]
, 2019 BackgroundGiven the high prevalence of chronic kidney disease (CKD), primary care physicians (PCPs) frequently manage early stage CKD. Nonetheless, there are challenges in providing optimal CKD care in the primary care setting.
Abdel-Kader, Khaled +15 more
core +1 more source
Bicarbonate Therapy for Critically Ill Patients with Metabolic Acidosis: A Systematic Review
Cureus, 2019 The management of acid-base disorders always calls for precise diagnosis and treatment of the underlying disease. Sometimes additional means are necessary to combat systemic acidity itself.
S. Ghauri +4 more
semanticscholar +1 more source
Scientific Reports, 2019 Metabolic acidosis is common in chronic kidney disease (CKD) and may have various deleterious consequences. Arterial stiffness in CKD patients is associated with poor cardiovascular outcomes.
H. Kim +8 more
semanticscholar +1 more source
Normal anion gap metabolic acidosis secondary to topiramate intake: case report
Case Reports, 2018 Introduction: Topiramate is a drug used to treat various types of epilepsy and as prophylaxis in cases of migrainous headache. One of its mechanisms of action is the inhibition of carbonic anhydrase in the kidney that triggers the excretion of alkaline ...
Jorge Fernando Miño-Bernal +3 more
doaj +1 more source
Primary assessment of patients admitted to the emergency ward using arterial blood gas
MGM Journal of Medical Sciences, 2022 Background: Arterial blood gas study (ABG) is a point-of-care testing (POCT) diagnostic tool that can furnish metabolic and respiratory aberrations. This study was conducted systematically, to assess the metabolic and respiratory aberrations quickly and ...
Sanjay Mulay +3 more
doaj +1 more source
Randomized preclinical study of machine perfusion in vascularized composite allografts
BJS (British Journal of Surgery), EarlyView., 2020 This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin +7 more
wiley +1 more source
Kidney International ReportsIntroduction: We investigated the relationship between metabolic acidosis over time and allograft outcome in pediatric kidney transplantation (KTx). Methods: This registry study collected data up to 10 years posttransplant.
Agnieszka Prytula +120 more
doaj +1 more source
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2020 Background Lentiform fork sign is a neuroradiological abnormality which is encountered in the clinical practice associated with uremic encephalopathy, dialysis disequilibrium syndrome and metabolic acidosis.
Salman Mansoor +10 more
doaj +1 more source
Metabolic Changes Following Perinatal Asphyxia: Role of Astrocytes and Their Interaction with Neurons [PDF]
, 2016 Perinatal Asphyxia (PA) represents an important cause of severe neurological deficits including delayed mental and motor development, epilepsy, major cognitive deficits and blindness.
Barreto, George E. +5 more
core +1 more source