Results 71 to 80 of about 1,243,890 (293)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Net proton influx into bone during metabolic, but not respiratory, acidosis

, 1988
During acute metabolic acidosis there is a net influx of protons into bone, decreasing the elevated proton concentration. Whether there is an influx of protons into bone during acute respiratory acidosis is not known.
D. A. Bushinsky
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Microenvironment‐Responsive Biomimetic Hydrogels Delivering Cistanche Deserticola‐Derived Nanovesicles for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
An injectable, microenvironment‐responsive hydrogel (HAPOCS@CDNVs) is developed for sustained delivery of Cistanche deserticola‐derived nanovesicles (CDNVs). By scavenging ROS, restoring mitochondrial function, and attenuating SASP, this platform effectively suppresses nucleus pulposus cell senescence and facilitates extracellular matrix reconstruction,
Ning Xu, Xiaoyu Cai, Xiaofu Tang, Weidong Liang, Linsong Teng, Yudong Jing, Haifeng Hu, Yuhao Duan, Mingjie Kuang, Lei Zhang, Shijie Han, Weibin Sheng   +11 more
wiley   +1 more source

Impact of mild hypercapnia in critically ill patients with metabolic acidosis [PDF]

Purpose Clinical trials focusing on critically ill patients with metabolic acidosis, a common exclusion criterion is the presence of a PaCO2 > 45 mmHg.
Attokaran, Antony G., Laupland, Kevin, Attokaran, Antony G, Luke, Stephen, Kumar, Aashish, Serpa Neto, Ary, Shekar, Kiran, Blank, Sebastiaan, Garrett, Peter, McCullough, James, Takahashi, Kazunari, Senthuran, Siva, Nasser, Ahmad, Fujii, Tomoko, Bellomo, Rinaldo, Marella, Prashanti, Tabah, Alexis, other, and, et al., https://orcid.org/, White, Kyle, McNamara, Mairead   +21 more
core   +1 more source

Implantable Systems for Cardiovascular Treatment and Monitoring: Comparative Insights From Intracardiovascular and Extracardiovascular Technologies

Advanced Intelligent Systems, EarlyView.
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò, Semproni Federica, Maselli Martina, Colli Andrea, Cianchetti Matteo, Ciuti Gastone, Stefanini Cesare, Menciassi Arianna   +7 more
wiley   +1 more source

COX14 Variants Are Associated With Mitochondrial Complex IV Deficiency Nuclear Type 10 (MC4DN10)

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT COX14 encodes a transmembrane protein essential for cytochrome c oxidase (COX) complex assembly. A homozygous missense variant in COX14 was reported in three siblings from a single consanguineous family with severe, fatal infantile mitochondrial complex IV deficiency nuclear type 10 (MC4DN10; MIM# 619053).
Elias K. Awad, Emily Waskow, Hari Tunuguntla, Joseph Spinner, Hanna J. Tadros, Lisa T. Emrick, Daniel G. Calame, Fernando Scaglia   +7 more
wiley   +1 more source

L‐Cysteine and N‐Acetylcysteine Supplementation Improves Clinical Outcome in a Patient With COXPD10

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT MTO1 is a nuclear gene that encodes a mitochondrial protein essential for modifying mitochondrial transfer RNAs (tRNAs) and stabilizing codon‐anticodon interactions to ensure accurate and efficient mitochondrial protein synthesis and oxidative phosphorylation.
Nishitha R. Pillai, Sara A. Elsbecker, Grace Bronken McCarthy, Kaitlin Weisshappel, Peter Karachunski, Fernando Scaglia   +5 more
wiley   +1 more source

Metabolic acidosis [PDF]

Postgraduate Medical Journal, 1998
M S, Darwich, W, Allaf
openaire   +3 more sources

Serum Anion Gap in Metabolic Acidosis

, 2009
METABOLIC ACIDOSIS, DEFINED AS A pathophysiologic state characterized by an arterial pH <7.35 in the absence of an elevated partial pressure of carbon dioxide in arterial blood (PaCO2), is a common finding in the critically ill neonate.
Ivy Mandell
core   +1 more source