Results 71 to 80 of about 978,834 (172)

Maximal exercise at high altitude does not exacerbate inflammation in the human brain

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study investigated arterial–internal jugular venous (IJV) exchange of cytokines in response to low‐intensity and maximal cycling exercise at sea level and following 6–8 days at 3800 m a.s.l. There was a shift towards net release of interleukin‐6 (IL‐6), interleukin‐8 (IL‐8), monocyte chemoattractant protein‐1 (MCP‐1) and ...
Hannah G. Caldwell   +11 more
wiley   +1 more source

Hypoxia‐induced vulnerability of the somatosensory nervous system

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

Acid base status of prevalent peritoneal dialysis patients

open access: yesBulletin de la Dialyse à Domicile, 2018
Acid-base status of patients on peritoneal dialysis is influenced by multiple factors. Metabolic acidosis is a common feature of chronic renal failure and dialysis treatment provides alkali in the dialysate in order to maintain a normal acid-base balance.
Raymond Azar, Vincent Coevoet
doaj   +1 more source

From hot tub to high altitude: The makings of a human physiology field expedition and the next generation of physiologists

open access: yes
Experimental Physiology, EarlyView.
M. M. Tymko   +4 more
wiley   +1 more source

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu   +2 more
wiley   +1 more source

On the generation, maintenance, and correction of metabolic alkalosis

open access: yes, 1983
The study of derangements in salt, water, and acid-base homeostasis frequently reveals much about renal transport mechanisms and their regulation. The study of one such derangement, metabolic alkalosis, has played a special role in contributing to our ...
H. R. Jacobson, D. W. Seldin
core   +1 more source

Spontaneous Hyperinflation of Intragastric Balloon Presenting as Acute Pancreatitis

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Obesity is a metabolic disorder with considerable health implications affecting populations worldwide. Intragastric balloon (IGB) placement has gained popularity as a minimally invasive and reversible management option for obesity. Although generally safe, IGBs can sometimes be associated with serious adverse outcomes. We present a case of IGB
Ong Yan Ling   +2 more
wiley   +1 more source

Association between metabolic alkalosis and 30-day respectively 12-month mortality.

open access: yes, 2017
Association between metabolic alkalosis and 30-day respectively 12-month mortality.
Amir Baigi (3611954)   +4 more
core   +1 more source

Long-term survival with congenital Bartter syndrome: A case report

open access: yesJournal of the Pakistan Medical Association
Bartter syndrome is a rare congenital salt-wasting renal tubular disorder, caused by defective salt reabsorption in the thick ascending limb of the loop of Henle.
Ghaffar Billoo   +5 more
doaj   +1 more source

Dual Urea Cycle Dysfunction Caused by Coexisting Argininosuccinic Aciduria and Citrin Deficiency: Clinical, Biochemical, and Molecular Insights From an Exceptional Case

open access: yesJIMD Reports, Volume 67, Issue 6, November 2026.
ABSTRACT Dual inherited defects affecting urea cycle function are exceptionally rare. We report the first case, to our knowledge, of the coexistence of argininosuccinic aciduria (ASA) and citrin deficiency (CD). A girl born to consanguineous Tunisian parents presented at 6 months of age with recurrent seizures, vomiting, developmental delay, and severe
Mouna Zribi   +6 more
wiley   +1 more source

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