Results 71 to 80 of about 697 (144)

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones

The Journal of Physiology, EarlyView.
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu, Eduardo Bravo, George Bradley Richerson   +2 more
wiley   +1 more source

Exercise hyperpnoea: Unravelling layers of regulation

The Journal of Physiology, EarlyView.
Abstract figure legend Intensity‐dependent changes in hypercapnic ventilatory response (HCVR) and feedforward gain (GEX) during exercise hyperpnoea below the respiratory compensation point (RCP). Participants (N = 20; 10 females) completed a 44 min step‐incremental cycling protocol in the moderate (below gas exchange threshold (GET)) and heavy ...
Nasimi A. Guluzade, Gordon S. Mitchell, Daniel A. Keir   +2 more
wiley   +1 more source

A patient with cystinosis presenting transient features of Bartter syndrome

The Turkish Journal of Pediatrics, 2006
A 16-month-old boy was admitted to the clinic because of vomiting and growth failure. His weight and height measurements were under the fifth percentile. He had fair hair and skin, enlarged wrists and rachitic rosaries.
Bilal Yildiz, Sultan Durmuş-Aydoğdu, Nurdan Kural, Kismet Bildirici, Hikmet Başmak, Coşkun Yarar   +5 more
doaj  

Profound Alkalosis and Prolonged QT Interval Due to Inappropriate Gastrostomy Tube Loss: A Case Report

Clinical Practice and Cases in Emergency Medicine
Introduction: Severe metabolic alkaloses are relatively rare but can carry a high mortality rate. Treatment involves supportive care and treatment of underlying causes.
Forrest Turner, Brandon Friedman, H. Pendell Meyers, Stephen W. Smith   +3 more
doaj   +1 more source

Bartter Syndrome Type 1 Presenting as Nephrogenic Diabetes Insipidus

Case Reports in Pediatrics, 2018
Bartter syndrome (BS) type 1 (OMIM #601678) is a hereditary salt-losing renal tubular disorder characterized by hypokalemic metabolic alkalosis, hypercalciuria, nephrocalcinosis, polyuria, recurrent vomiting, and growth retardation.
Gianluca Vergine, Elena Fabbri, Annalisa Pedini, Silvana Tedeschi, Niccolò Borsa   +4 more
doaj   +1 more source

From hot tub to high altitude: The makings of a human physiology field expedition and the next generation of physiologists

Experimental Physiology, EarlyView.
M. M. Tymko, K. J. Smith, A. R. Bain, I. A. Fernandes, B. S. Stacey   +4 more
wiley   +1 more source

Early prediction of multiple organ failure for sepsis patients based on machine learning algorithms

Journal of Intelligent Medicine, Volume 3, Issue 3, Page 277-289, September 2026.
Abstract In recent years, there has been a notable rise in sepsis incidence leading to more multiple organ failure and higher mortality. The lack of effective treatments for sepsis highlights the importance of early prediction in preventing multiple organ failure. This study aimed to develop a model for the early prediction of multiple organ failure in
Runnan He, Nan Su, Yuqing Wang, Yulin Sun, Xin Weng, Tania Pereira, Chenggong Hu, Keliang Xie, Meijun Pang, Kuo Zhang, Chuanxiang Huang, Xiuyun Liu   +11 more
wiley   +1 more source

Hypercalcemia-Induced Hypokalemic Metabolic Alkalosis in a Multiple Myeloma Patient: The Risk of Furosemide Use

Case Reports in Oncology, 2015
Hypercalcemia is often seen in patients with malignancies, and in the past treatment for this has traditionally included loop diuretics. Clinically, patients with hypercalcemia frequently present with polyuria and volume contraction which may be further ...
Ira W. Reiser, Slamat Ali, Vladimir Gotlieb, Samuel Spitalewitz   +3 more
doaj   +1 more source

Impaired Renal Base Excretion in Secretin Receptor Knock‐Out Mice During Prolonged Base‐Loading

Acta Physiologica, Volume 242, Issue 9, September 2026.
ABSTRACT Aim Secretin was recently found to play a pivotal role in the renal adaptation to acute base excess. Here, secretin increases pendrin‐dependent HCO3− secretion from the beta‐intercalated cells in the cortical collecting ducts. Whether secretin and its receptor play a role during prolonged base‐loading remains unknown.
Tobias Jensen, Jesper Frank Andersen, Laura Woidemann Trans, Ida Marie Modvig, Helga Vitzthum, Jens Juul Holst, Bolette Hartman, Samuel L. Svendsen, Mads Vaarby Sørensen, Jens Leipziger, Peder Berg   +10 more
wiley   +1 more source

Beyond right or wrong: How partial credit scoring on multiple‐choice questions improves student performance and assessment perceptions

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2542-2548, August 2026.
Aims In this study, we examined the effects of assigning partial credit to selected answer choices on student performance and perceptions in a pharmacology course using Type A multiple‐choice questions (MCQs). Methods Partial credit scoring was incorporated into quizzes and exams in a 10‐week pharmacology course for postbaccalaureate premedical ...
Stephen D. Schneid, Chris Armour, Katharina Brandl   +2 more
wiley   +1 more source