Results 21 to 30 of about 903,544 (342)

Exosomes and Obesity-Related Insulin Resistance

Frontiers in Cell and Developmental Biology, 2021
Exosomes are extracellular vesicles, delivering signal molecules from donor cells to recipient cells. The cargo of exosomes, including proteins, DNA and RNA, can target the recipient tissues and organs, which have an important role in disease development.
Li-Min Lei, Xiao Lin, Feng Xu, Su-Kang Shan, Bei Guo, Fu-Xing-Zi Li, Ming-Hui Zheng, Yi Wang, Qiu-Shuang Xu, Ling-Qing Yuan   +9 more
doaj   +1 more source

ZEB1 Mediates Bone Marrow Mesenchymal Stem Cell Osteogenic Differentiation Partly via Wnt/β-Catenin Signaling

Frontiers in Molecular Biosciences, 2021
Zinc finger E-box-binding homebox 1 (ZEB1) is a zinc-finger transcription factor best known for its role in promoting the epithelial-mesenchymal transition, which is also related to osteogenesis. Here, ZEB1 was investigated for its role in the commitment
Cuidi Xu, Hongli Shi, Xin Jiang, Yongqian Fan, Donghui Huang, Xinming Qi, Qun Cheng   +6 more
doaj   +1 more source

Osteopontin in Bone Metabolism and Bone Diseases [PDF]

Medical Science Monitor, 2020
Osteopontin (OPN), a secreted phosphoprotein, is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family of cell matrix proteins and participates in many biological activities. Studies have shown that OPN plays a role in bone metabolism and homeostasis.
Si, Jinyan, Wang, Chaowei, Zhang, Denghui, Wang, Bo, Hou, Weiwei, Zhou, Yi   +5 more
openaire   +2 more sources

Voriconazole-induced periostitis

Reumatismo, 2021
Voriconazole is a fluorinated drug from the triazole group that is widely used in the prophylaxis and treatment of fungal infections in immunosuppressed patients. Chronic use of this medication can generate, as an adverse effect, a multifocal, asymmetric,
D.C. Fernández Ávila, M. Diehl, A.M. Degrave, M. Buttazzoni, T. Pereira, M.A. Aguirre, A.L. Basquiera, M. Scolnik   +7 more
doaj   +1 more source

Factors associated to serum 25-hydroxyvitamin D levels among older adult populations in urban and suburban communities in Shanghai, China

BMC Geriatrics, 2017
Background Vitamin D deficiency is widespread in China, particularly among older adults. Factors associated with suboptimal vitamin D levels are not well defined.
Qun Cheng, Yanping Du, Wei Hong, Wenjing Tang, Huilin Li, Minmin Chen, Songbai Zheng   +6 more
doaj   +1 more source

The Interplay Between the Renin-Angiotensin-Aldosterone System and Parathyroid Hormone

Frontiers in Endocrinology, 2020
The renin-angiotensin-aldosterone system (RAAS) is the regulatory system by which renin induces aldosterone production. Angiotensin II (Ang II) is the main effector substance of the RAAS.
Ming-Hui Zheng, Fu-Xing-Zi Li, Feng Xu, Xiao Lin, Yi Wang, Qiu-Shuang Xu, Bei Guo, Ling-Qing Yuan   +7 more
doaj   +1 more source

Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis

Scientific Reports, 2021
Loss of function (LOF) in IL11RA infers IL11 signaling as important for fertility, fibrosis, inflammation and incompletely penetrant craniosynostosis. The impact of LOF in IL11 has not been characterized.
Benjamin Ng, Anissa A. Widjaja, Sivakumar Viswanathan, Jinrui Dong, Sonia P. Chothani, Stella Lim, Shamini G. Shekeran, Jessie Tan, Narelle E. McGregor, Emma C. Walker, Natalie A. Sims, Sebastian Schafer, Stuart A. Cook   +12 more
doaj   +1 more source

The Role of Substance P in the Regulation of Bone and Cartilage Metabolic Activity

Frontiers in Endocrinology, 2020
Substance P (SP) is a neuropeptide that is released from sensory nerve endings and is widely present in nerve fibers. It acts on bones and related tissues by binding to receptors, thereby regulating bone metabolism, cartilage metabolism, and fracture ...
Fu-Xing-Zi Li, Feng Xu, Xiao Lin, Feng Wu, Jia-Yu Zhong, Yi Wang, Bei Guo, Ming-Hui Zheng, Su-Kang Shan, Ling-Qing Yuan   +9 more
doaj   +1 more source

Muscle and Bone Impairment in Infantile Nephropathic Cystinosis: New Concepts

Cells, 2022
Cystinosis Metabolic Bone Disease (CMBD) has emerged during the last decade as a well-recognized, long-term complication in patients suffering from infantile nephropathic cystinosis (INC), resulting in significant morbidity and impaired quality of life ...
Dieter Haffner, Maren Leifheit-Nestler, Candide Alioli, Justine Bacchetta   +3 more
doaj   +1 more source

Bone Turnover Markers in the Diagnosis and Monitoring of Metabolic Bone Disease.

Clinical Chemistry, 2017
BACKGROUND Disorders of bone metabolism, most notably osteoporosis, are highly prevalent and predispose to fractures, causing high patient morbidity and mortality.
M. Greenblatt, J. Tsai, Marc N. Wein
semanticscholar   +1 more source