Results 1 to 10 of about 1,118,702 (266)
BMC Geriatrics, 2021 Background Osteoporosis and sarcopenia are major health issues in postmenopausal women due to their high prevalence and association with several adverse outcomes. However, no biomarkers may be used for screening and diagnosis.
Yanping Du +9 more
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Medicina, 2022 Background and Objectives: Oxytocin (OT) is a neuropeptide hormone which is known for its classical effects in pregnancy and lactation. Recently, growing evidence demonstrated a close relation between OT and bone.
Wei-Jia Yu +9 more
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Osteopontin in Bone Metabolism and Bone Diseases [PDF]
Medical Science Monitor, 2020 Osteopontin (OPN), a secreted phosphoprotein, is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family of cell matrix proteins and participates in many biological activities. Studies have shown that OPN plays a role in bone metabolism and homeostasis.
Si, Jinyan +5 more
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Frontiers in Endocrinology, 2021 ObjectiveThe current study was conducted to determine whether peak bone mineral density (BMD) and obesity phenotypes are associated with certain LGR4 gene polymorphisms found in Chinese nuclear families with female children.MethodsA total of 22 single ...
Su-qin Shi +10 more
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Eldecalcitol prevents muscle loss by suppressing PI3K/AKT/FOXOs pathway in orchiectomized mice
Frontiers in Pharmacology, 2022 Elderly male patients are susceptible to develop osteoporosis and sarcopenia, especially those with fragility fractures, hypogonadism, and prostate cancer with androgen deprivation therapy.
Haichao Zhang +7 more
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Skeletal Muscle, 2023 We investigated the effect of eldecalcitol on disuse muscle atrophy. C57BL/6J male mice aged 6 weeks were randomly assigned to control, tail suspension (TS), and TS-eldecalcitol–treated groups and were injected intraperitoneally twice a week with either ...
Haichao Zhang +7 more
doaj +1 more source
Adynamic bone disease--bone and beyond [PDF]
Clinical Kidney Journal, 2008 Disturbances of bone and mineral metabolism are a hallmark of chronic kidney disease (CKD). Renal osteodystrophy (ROD) is the traditional term for bone lesions in conjunction with CKD and is now considered a part of the ‘chronic kidney disease—mineral and bone disorder’ (CKD-MBD) [1].
Brandenburg, Vincent M., Floege, Jürgen
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Novel mutations in BMP1 result in a patient with autosomal recessive osteogenesis imperfecta
Molecular Genetics & Genomic Medicine, 2021 Background Osteogenesis imperfecta (OI) is a rare heritable bone disorder that is characterised by increased bone fragility and recurrent fractures. To date, only 19 OI patients have been reported, as caused by BMP1 gene mutations, worldwide.
Lei Xi +3 more
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Journal of Translational Medicine, 2023 Background Ankylosing spondylitis (AS) is an autoimmune disease with a genetic correlation and is characterized by inflammation in the axial skeleton and sacroiliac joints.
Xinzhe Feng +5 more
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Persistent vs Recurrent Cushing’s Disease Diagnosed Four Weeks Postpartum
Case Reports in Endocrinology, 2022 Background. Cushing’s disease (CD) recurrence in pregnancy is thought to be associated with estradiol fluctuations during gestation. CD recurrence in the immediate postpartum period in a patient with a documented dormant disease during pregnancy has ...
Leena Shah +3 more
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