Results 31 to 40 of about 1,118,702 (266)
International Journal of Endocrinology, 2013 The reference ranges of bone turnover markers (BTMs) were important during the treatment of osteoporosis, and the associations with bone mineral density (BMD) were controversial.
Wei-Wei Hu +8 more
doaj +1 more source
FGF19 increases mitochondrial biogenesis and fusion in chondrocytes via the AMPKα-p38/MAPK pathway
Cell Communication and Signaling, 2023 Fibroblast growth factor 19 (FGF19) is recognized to play an essential role in cartilage development and physiology, and has emerged as a potential therapeutic target for skeletal metabolic diseases.
Shiyi Kan +11 more
doaj +1 more source
Primary hypertrophic osteoarthropathy: genetics, clinical features and management
Frontiers in Endocrinology, 2023 Primary hypertrophic osteoarthropathy (PHO) is a genetic disorder mainly characterized by clubbing fingers, pachydermia and periostosis. Mutations in the HPGD or SLCO2A1 gene lead to impaired prostaglandin E2 (PGE2) degradation, thus elevating PGE2 ...
Qi Lu +4 more
doaj +1 more source
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
Pediatric Blood &Cancer, EarlyView.ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
Aging MedicineObjectives Low skeletal muscle mass is associated with adverse clinical outcomes. Due to constraints related to cost and equipment availability, direct measurement of skeletal muscle mass is often not feasible in routine practice.
Minmin Chen +6 more
doaj +1 more source
Diagnosis and Treatment of Polycythemia Vera in Pakistan; Barriers and Possible Solutions [PDF]
Liaquat National Journal of Primary CareThis review aims to highlight the challenges encountered in managing Polycythemia Vera in resource-limited settings and to suggest a cost-effective strategy for timely diagnosis and treatment.
Rabab Jafry +4 more
doaj +1 more source
Journal of Orthopaedic Surgery and Research, 2023 Background Circular RNAs (circRNAs) are important regulators on the onset and progression of rheumatoid arthritis (RA). Our purpose is to explore the role and underpin mechanism of circ_0000396 in RA progression.
Hongchao Yu +4 more
doaj +1 more source
Neuromuscular Diseases and Bone
Frontiers in Endocrinology, 2019 Neuromuscular diseases (NMDs) are inherited or acquired conditions affecting skeletal muscles, motor nerves, or neuromuscular junctions. Most of them are characterized by a progressive damage of muscle fibers with reduced muscle strength, disability, and poor health-related quality of life of affected patients.
Iolascon G +4 more
openaire +4 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita +5 more
wiley +1 more source