3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
Advanced Functional Materials, EarlyView.A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source
Does metabolic bone disease follow truncal vagotomy and gastrojejunostomy? [PDF]
, 1983 Andy Irving, GR Smith, G.R.D. Catto
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Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix
Advanced Functional Materials, EarlyView.Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt +2 more
wiley +1 more source
Age trend and risk factors of height loss in Chinese over 40 years old
Frontiers in EndocrinologyIntroductionTo evaluate age-related height loss trend in men and women in China, and analyze associated risk factors, we conducted a cross-sectional study among 1286 participants from the Bone Health Improvement Program.MethodsLaboratory data were ...
Yong-Fang Li +6 more
doaj +1 more source
Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation
Advanced Functional Materials, EarlyView.Organic photovoltaic electrodes based on the D18:Y6 blend enable precise and light‐controlled activation of retinal ganglion cells in a degenerating retina. NIR Light‐driven activation of retinal ganglion cells, tunable stimulation parameters, and biocompatibility with human retinal organoids highlight their potential for next‐generation prosthetics ...
Andrea Corna +10 more
wiley +1 more source
Tailoring the Properties of Functional Materials With N‐Oxides
Advanced Functional Materials, EarlyView.The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich +5 more
wiley +1 more source
Metabolic effects of pamidronate in patients with metastatic bone disease [PDF]
, 1996 J. Vinholes +4 more
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Advanced Functional Materials, EarlyView.This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv +10 more
wiley +1 more source
Preoperative medical therapy for acromegaly: current knowledge and clinical significance
Frontiers in EndocrinologyAcromegaly is a chronic endocrine disorder characterized by excessive secretion of growth hormone (GH), predominantly caused by pituitary adenomas. Despite advancements in neurosurgical techniques, the surgical remission rates for invasive macroadenomas ...
Dan He +3 more
doaj +1 more source
Therapeutic Management in a Tortoise Affected Concurrently with Metabolic Bone Disease and Respiratory Infection-A Case Report [PDF]
, 2020 Rajkumar Patel, Rajesh Patel
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