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Global burden of metabolic diseases, 1990–2021
Metabolism: Clinical and ExperimentalBACKGROUND Common metabolic diseases, such as type 2 diabetes mellitus (T2DM), hypertension, obesity, hypercholesterolemia, and metabolic dysfunction-associated steatotic liver disease (MASLD), have become a global health burden in the last three decades.
John D Ryan
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Extracellular Vesicles in Metabolism and Metabolic Diseases
2021No description supplied
Akbar L, Marzan +2 more
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Cataract and metabolic disease
Journal of Inherited Metabolic Disease, 1990SummaryIn addition to the already recognized metabolic diseases which have been associated with cataract formation, e.g. galactosaemia, galactokinase deficiency, Lowe's syndrome and diabetes, several other disorders can also lead to the development of cataracts.
W, Endres, Y S, Shin
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Journal of Child Neurology, 2008
Autism is an etiologic heterogeneous entity caused by many different diseases occurring in the central nervous system at an early stage in life. Several metabolic defects have been associated with autistic symptoms with a rate higher than that found in the general population.
Manzi, B +3 more
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Autism is an etiologic heterogeneous entity caused by many different diseases occurring in the central nervous system at an early stage in life. Several metabolic defects have been associated with autistic symptoms with a rate higher than that found in the general population.
Manzi, B +3 more
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Epitranscriptomics in metabolic disease
Nature Metabolism, 2023While epigenetic modifications of DNA and histones play main roles in gene transcription regulation, recently discovered post-transcriptional RNA modifications, known as epitranscriptomic modifications, have been found to have a profound impact on gene expression by regulating RNA stability, localization and decoding efficiency.
Yoshihiro Matsumura +2 more
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The role of ferroptosis in metabolic diseases.
Biochimica et biophysica acta. Molecular cell research, 2023The annual incidence of metabolic diseases such as diabetes, non-alcoholic fatty liver disease (NAFLD), osteoporosis, and atherosclerosis (AS) is increasing, resulting in a heavy burden on human health and the social economy.
Ling Xie, Bin Fang, Chun Zhang
semanticscholar +1 more source
Endocrine, 2017
Irisin is a myokine/adipokine induced by the exercise in mice and humans, which is proposed to induce "browning" of white adipose tissue, its primary target, thus increasing thermogenesis and energy expenditure. Since its identification, irisin has been linked to favorable effects on metabolic diseases, including obesity, type 2 diabetes mellitus (T2DM)
Stergios A, Polyzos +6 more
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Irisin is a myokine/adipokine induced by the exercise in mice and humans, which is proposed to induce "browning" of white adipose tissue, its primary target, thus increasing thermogenesis and energy expenditure. Since its identification, irisin has been linked to favorable effects on metabolic diseases, including obesity, type 2 diabetes mellitus (T2DM)
Stergios A, Polyzos +6 more
openaire +2 more sources
Regulation of bile acids and their receptor FXR in metabolic diseases
Frontiers in NutritionHigh sugar, high-fat diets and unhealthy lifestyles have led to an epidemic of obesity and obesity-related metabolic diseases, seriously placing a huge burden on socio-economic development. A deeper understanding and elucidation of the specific molecular
Yao Li +4 more
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The health benefits of dietary short-chain fatty acids in metabolic diseases
Critical reviews in food science and nutritionShort-chain fatty acids (SCFAs) are a subset of fatty acids that play crucial roles in maintaining normal physiology and developing metabolic diseases, such as obesity, diabetes, cardiovascular disease, and liver disease.
Zhipeng Tao, Yao Wang
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Metabolic diseases and pregnancy
Clinics in Dermatology, 2006The skin mirrors the hormonal metabolic and physiologic changes that occur during pregnancy. The metabolic effects are manifested primarily in accentuation of two disorders, porphyria cutanea tarda and acrodermatitis enteropathica. The former may be exacerbated, not only during pregnancy, but also during the post-partum period and with the intake of ...
Adrián, Pérez-Maldonado +1 more
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