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Miscellaneous metabolic diseases
Current Opinion in Rheumatology, 1996Musculoskeletal manifestations are commonly observed in metabolic disorders. Here we review the recent literature on several metabolic arthropathies. Hemochromatosis should be suspected in patients with the sign of the "iron salute". Screening for this disorder by routine measurement of transferrin saturation appears to be a cost-effective procedure in
D, Van Linthoudt, A K, So
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Current Opinion in Gastroenterology, 2000
This review focuses on two genetic disorders of metal metabolism, genetic hemochromatosis and Wilson disease, and on the most common lysosomal storage disorder, Gaucher disease, for which recombinant enzyme replacement therapy is available. The discovery of the genes for these disorders has led to an explosion of new information about the function of ...
M L, Schilsky, P, Mistry
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This review focuses on two genetic disorders of metal metabolism, genetic hemochromatosis and Wilson disease, and on the most common lysosomal storage disorder, Gaucher disease, for which recombinant enzyme replacement therapy is available. The discovery of the genes for these disorders has led to an explosion of new information about the function of ...
M L, Schilsky, P, Mistry
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Ubiquitination and Metabolic Disease
The increasing incidence of metabolic diseases, including obesity, type 2 diabetes mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD), in the past decade is a serious concern worldwide. Disruption of cellular protein homeostasis has been considered as a crucial contributor to the pathogenesis of metabolic diseases.Meilin, Ma +3 more
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Seminars in Musculoskeletal Radiology, 2002
Rickets is a metabolic bone disorder characterized by osteopenic changes resulting from the failure of calcification of the osteoid matrix and absent mineralization of hypertrophic cartilage cells at the epiphyseal growth plates in growing primates, herbivores, swine, carnivores, and birds.
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Rickets is a metabolic bone disorder characterized by osteopenic changes resulting from the failure of calcification of the osteoid matrix and absent mineralization of hypertrophic cartilage cells at the epiphyseal growth plates in growing primates, herbivores, swine, carnivores, and birds.
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Metabolism and Alzheimer's Disease
2003Many abnormalities have been described in the brains of patients with Alzheimer’s disease (AD), particularly in tissue obtained at autopsy. AD patients usually die in late stages of the disease, although sometimes other illnesses or accidents lead to death in early AD. Abnormalities in autopsy brain can be the result of agonal and postmortem artifacts.
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JAMA: The Journal of the American Medical Association, 1979
ABSTRACT The second volume of Metabolic Bone Disease contains seven additional essays on bone and mineral metabolism. Despite the book's title, there is in many instances a scarcity of information on bone disease. Topics previously covered in the first volume do, however, make up for this deficit to some extent.The chapter on parathyroid physiology and
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ABSTRACT The second volume of Metabolic Bone Disease contains seven additional essays on bone and mineral metabolism. Despite the book's title, there is in many instances a scarcity of information on bone disease. Topics previously covered in the first volume do, however, make up for this deficit to some extent.The chapter on parathyroid physiology and
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Clinics and Research in Hepatology and Gastroenterology, 2012
Diagnosis of metabolic liver disease requires a high level of diagnostic suspicion. Diet is usually the primary treatment for metabolic liver disease. Where indicated, liver transplantation provides lifelong functional correction of liver-based metabolic defects.
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Diagnosis of metabolic liver disease requires a high level of diagnostic suspicion. Diet is usually the primary treatment for metabolic liver disease. Where indicated, liver transplantation provides lifelong functional correction of liver-based metabolic defects.
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Hospital Medicine, 2003
Eye involvement is a feature of many metabolic diseases; early identification of ocular changes may aid diagnosis and management of the underlying condition. This review aims to describe common metabolic conditions where ocular findings can help the diagnosis.
Ayman, al-Khaier, Ken K, Nischal
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Eye involvement is a feature of many metabolic diseases; early identification of ocular changes may aid diagnosis and management of the underlying condition. This review aims to describe common metabolic conditions where ocular findings can help the diagnosis.
Ayman, al-Khaier, Ken K, Nischal
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Alzheimer’s as a metabolic disease
Biogerontology, 2013Empirical evidence indicates that impaired mitochondrial energy metabolism is the defining characteristic of almost all cases of Alzheimer's disease (AD). Evidence is reviewed supporting the general hypothesis that the up-regulation of OxPhos activity, a metabolic response to mitochondrial dysregulation, drives the cascade of events leading to AD. This
Lloyd A, Demetrius, Jane, Driver
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