Results 41 to 50 of about 1,841,015 (211)

Cationic Polystyrene Resolves Nonalcoholic Steatohepatitis, Obesity, and Metabolic Disorders by Promoting Eubiosis of Gut Microbiota and Decreasing Endotoxemia. [PDF]

open access: yes, 2017
A pandemic of metabolic diseases, consisting of type 2 diabetes, nonalcoholic fatty liver disease, and obesity, has imposed critical challenges for societies worldwide, prompting investigation of underlying mechanisms and exploration of low-cost and ...
Bai, Li   +22 more
core   +1 more source

Association between Serum Magnesium and Hemoglobin in Patients with Primary Hyperparathyroidism

open access: yesInternational Journal of Endocrinology, 2021
Background. There is a positive association between serum magnesium and hemoglobin levels in the general population. However, no studies have evaluated the association between serum magnesium and hemoglobin levels in patients with primary ...
Na Ding   +8 more
doaj   +1 more source

Effect of short-term probiotic Enterococcus faecium SF68 dietary supplementation in overweight and obese cats without comorbidities [PDF]

open access: yes, 2016
Obesity in cats is associated with metabolic abnormalities and increased susceptibility to diseases such as diabetes mellitus. Studies in mouse models and human beings have shown that probiotics can reduce food intake, promote weight loss and improve ...
Fascetti, A J   +3 more
core   +1 more source

Sphingolipid metabolism diseases

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2006
Human diseases caused by alterations in the metabolism of sphingolipids or glycosphingolipids are mainly disorders of the degradation of these compounds. The sphingolipidoses are a group of monogenic inherited diseases caused by defects in the system of lysosomal sphingolipid degradation, with subsequent accumulation of non-degradable storage material ...
Kolter, Thomas, Sandhoff, Konrad
openaire   +2 more sources

BMP9 reduces age-related bone loss in mice by inhibiting osteoblast senescence through Smad1-Stat1-P21 axis

open access: yesCell Death Discovery, 2022
BMP9 inhibits cellular senescence by activation of Smad1, which suppresses the transcription of Stat1, resulting in decreased P21 expression and SASPs production in osteoblast.
Jing-zun Xu   +11 more
doaj   +1 more source

Modulation of PGC-1α activity as a treatment for metabolic and muscle-related diseases [PDF]

open access: yes, 2014
Physical inactivity is a predisposing factor for various disease states including obesity, cardiovascular disease, as well as for certain types of cancer. Regular endurance exercise mediates several beneficial effects such as increased energy expenditure
Handschin, Christoph   +1 more
core   +1 more source

与糖尿病相关的家族史, 生活方式和代谢危险因素的全面风险描述:一项前瞻性队列研究

open access: yesJournal of Diabetes, 2022
Background Family history of diabetes, unhealthy lifestyles, and metabolic disorders are individually associated with higher risk of diabetes, but how different combinations of the three risk categories are associated with incident diabetes remains ...
Chaojie Ye   +14 more
doaj   +1 more source

Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]

open access: yes, 2017
Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
core   +2 more sources

RNA regulation of lipotoxicity and metabolic stress [PDF]

open access: yes, 2016
Noncoding RNAs are an emerging class of nonpeptide regulators of metabolism. Metabolic diseases and the altered metabolic environment induce marked changes in levels of microRNAs and long noncoding RNAs.
Caputa, George, Schaffer, Jean E
core   +2 more sources

Osteocalcin Levels in Male Idiopathic Hypogonadotropic Hypogonadism: Relationship With the Testosterone Secretion and Metabolic Profiles

open access: yesFrontiers in Endocrinology, 2019
Idiopathic hypogonadotropic hypogonadism (IHH) patients are characterized by the absence of puberty and varying degrees of deteriorated metabolic conditions.
Yu-Ying Yang   +14 more
doaj   +1 more source

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