Results 21 to 30 of about 1,208,819 (269)

Fat mass to fat-free mass ratio and the risk of non-alcoholic fatty liver disease and fibrosis in non-obese and obese individuals

open access: yesNutrition & Metabolism, 2021
Context Body composition may explain partially why non-obese individuals still at the risk of developing non-alcoholic fatty liver disease (NAFLD).
Huajie Dai   +13 more
doaj   +1 more source

Age-specific prevalence, subtypes and risk factors of metabolic diseases in Chinese adults and the different patterns from other racial/ethnic populations

open access: yesBMC Public Health, 2022
Background Age has substantial influence on metabolic diseases patterns. Ethnic disparities of metabolic characteristics between Chinese and other populations also exist. Large-scale investigations of age-specific prevalence, subtypes and modifiable risk
Qiuyu Cao   +16 more
doaj   +1 more source

Opposite causal effects of birthweight on myocardial infarction and atrial fibrillation and the distinct mediating pathways: a Mendelian randomization study

open access: yesCardiovascular Diabetology, 2023
Background Previous observational studies have documented an inverse association of birthweight with myocardial infarction (MI) but a positive association with atrial fibrillation (AF).
Lijie Kong   +17 more
doaj   +1 more source

Dissecting Causal Relationships Between Gut Microbiota, Blood Metabolites, and Stroke: A Mendelian Randomization Study [PDF]

open access: yesJournal of Stroke, 2023
Background and Purpose We investigated the causal relationships between the gut microbiota (GM), stroke, and potential metabolite mediators using Mendelian randomization (MR).
Qi Wang   +17 more
doaj   +1 more source

METABOLISM AND MOUTH-DISEASE [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1910
Since there is a very close relationship between the functions of the various organs of the body, it is not unreasonable to suppose that disorganization in one part will be accompanied or followed by disturbances elsewhere. From a study of conditions as they are to-day in both medicine and dentistry, however, it would seem that this important fact is ...
openaire   +3 more sources

Sodium butyrate potentiates insulin secretion from rat islets at the expense of compromised expression of β cell identity genes

open access: yesCell Death and Disease, 2022
Short-chain fatty acids (SCFAs) produced by the gut microbiota have been well demonstrated to improve metabolic homeostasis. However, the role of SCFAs in islet function remains controversial.
Shushu Wang   +11 more
doaj   +1 more source

Sexual dimorphism in glucose metabolism is shaped by androgen-driven gut microbiome

open access: yesNature Communications, 2021
Male sex is a risk factor for impaired glucose metabolism and type 2 diabetes. Here the authors identify that androgen modulates the gut microbiome, which drives insulin resistance and contributes to sexual dimorphism in glucose metabolism in mice.
Aibo Gao   +20 more
doaj   +1 more source

Promoting metabolic inefficiency for metabolic disease

open access: yesiScience, 2023
Recent advances in pharmacotherapies that promote appetite suppression have shown remarkable weight loss. Therapies targeting energy expenditure lag behind, and as such none have yet been identified to be safe and efficacious for sustaining negative energy balance toward weight loss.
openaire   +3 more sources

血清低密度脂蛋白胆固醇浓度与糖尿病风险之间的关联: 一项前瞻性队列研究

open access: yesJournal of Diabetes, 2023
Background Low‐density lipoprotein cholesterol (LDL‐C) and diabetes mellitus are both modifiable risk factors for cardiovascular disease; however, whether elevated LDL‐C levels confer a risk for diabetes remains unclear. Objective We aimed to examine the
Jiaojiao Huang   +13 more
doaj   +1 more source

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