Results 21 to 30 of about 1,151,626 (269)
Roczniki Panstwowego Zakladu Higieny, 2019 Background. It has been established that in Type 1 Diabetes Mellitus (T1DM), regardless of the insulin therapy model used, diet and proper eating habits are still important in the treatment of the disease.
Sabina Krzyżowska +5 more
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MicroRNAs in Metabolic Disease [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2013 Alterations in the metabolic control of lipid and glucose homeostasis predispose an individual to develop cardiometabolic diseases, such as type 2-diabetes mellitus and atherosclerosis. Work over the last years has suggested that microRNAs (miRNAs) play an important role in regulating these physiological processes.
Carlos, Fernández-Hernando +3 more
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CBP/p300 HAT maintains the gene network critical for β cell identity and functional maturity
Cell Death and Disease, 2021 Loss of β cell identity and functional immaturity are thought to be involved in β cell failure in type 2 diabetes. CREB-binding protein (CBP) and its paralogue p300 act as multifunctional transcriptional co-activators and histone acetyltransferases (HAT)
Linlin Zhang +12 more
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Scientific Reports, 2017 Abnormal nutrient metabolism is a hallmark of aging, and the underlying genetic and nutritional framework is rapidly being uncovered, particularly using C. elegans as a model. However, the direct metabolic consequences of perturbations in life history of
Arwen W. Gao +13 more
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Journal of Translational Medicine, 2023 Background Observational studies and conventional Mendelian randomization (MR) studies showed inconclusive evidence to support the association between omega-3 fatty acids and type 2 diabetes. We aim to evaluate the causal effect of omega-3 fatty acids on
Chunyan Hu +21 more
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METABOLISM AND MOUTH-DISEASE [PDF]
JAMA: The Journal of the American Medical Association, 1910 Since there is a very close relationship between the functions of the various organs of the body, it is not unreasonable to suppose that disorganization in one part will be accompanied or followed by disturbances elsewhere. From a study of conditions as they are to-day in both medicine and dentistry, however, it would seem that this important fact is ...
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Cell Death and Disease, 2022 Short-chain fatty acids (SCFAs) produced by the gut microbiota have been well demonstrated to improve metabolic homeostasis. However, the role of SCFAs in islet function remains controversial.
Shushu Wang +11 more
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Promoting metabolic inefficiency for metabolic disease
iScience, 2023 Recent advances in pharmacotherapies that promote appetite suppression have shown remarkable weight loss. Therapies targeting energy expenditure lag behind, and as such none have yet been identified to be safe and efficacious for sustaining negative energy balance toward weight loss.
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Cardiovascular Diabetology, 2023 Background Glycemic variability plays an important role in the development of cardiovascular disease (CVD). This study aims to determine whether long-term visit-to-visit glycemic variability is associated with aortic stiffness progression in participants
Qianhua Fang +11 more
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