Results 1 to 10 of about 12,548,139 (260)
Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study
Signal Transduction and Targeted Therapy, 2023 Epigenetics regulates gene expression and has been confirmed to play a critical role in a variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease (NAFLD), osteoporosis, gout, hyperthyroidism, hypothyroidism and others.
Yan-Lin Wu +2 more
exaly +2 more sources
Nutrients, 2021 Metabolic diseases are serious threats to public health and related to gut microbiota. Probiotics, prebiotics, synbiotics, and postbiotics (PPSP) are powerful regulators of gut microbiota, thus possessing prospects for preventing metabolic diseases ...
Hang-Yu Li, Dan-Dan Zhou, Ren-You Gan
exaly +2 more sources
Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China
Clinical Research in Cardiology, 2020 Background Studies have reminded that cardiovascular metabolic comorbidities made patients more susceptible to suffer 2019 novel corona virus (2019-nCoV) disease (COVID-19), and exacerbated the infection.
Lili Zhi, Xiqian Wang, Lin Liu
exaly +2 more sources
Akkermansia muciniphila: a potential candidate for ameliorating metabolic diseases
Frontiers in ImmunologyMetabolic diseases are comprehensive disease based on obesity. Numerous cumulative studies have shown a certain correlation between the fluctuating abundance of Akkermansia muciniphila and the occurrence of metabolic diseases. A. muciniphila, a potential
Fengxia Liang, Xiaoyun Xu, Cui Dandan
exaly +2 more sources
Akkermansia muciniphila : is it the Holy Grail for ameliorating metabolic diseases?
Gut Microbes, 2021 The increasing prevalence of metabolic diseases has become a severe public health problem. Gut microbiota play important roles in maintaining human health by modulating the host’s metabolism.
Juan Yan, Lili Sheng, Houkai Li
exaly +2 more sources
Ferroptosis at the nexus of metabolism and metabolic diseases
TheranosticsFerroptosis, an iron-dependent form of regulated cell death, is emerging as a crucial regulator of human physiology and pathology. Increasing evidence showcases a reciprocal relationship between ferroptosis and dysregulated metabolism, propagating a pathogenic vicious cycle that exacerbates pathology and human diseases, particularly metabolic disorders.
Li, Shuangwen +4 more
openaire +3 more sources
The role of the gut microbiome and its metabolites in metabolic diseases
Protein and Cell, 2020 It is well known that an unhealthy lifestyle is a major risk factor for metabolic diseases, while in recent years, accumulating evidence has demonstrated that the gut microbiome and its metabolites also play a crucial role in the onset and development of
Xue-Mei Wang +2 more
exaly +2 more sources
Metabolic memory: mechanisms and diseases
Signal Transduction and Targeted TherapyMetabolic diseases and their complications impose health and economic burdens worldwide. Evidence from past experimental studies and clinical trials suggests our body may have the ability to remember the past metabolic environment, such as hyperglycemia ...
Lulingxiao Nie +2 more
exaly +2 more sources
Retinal Disease and Metabolism [PDF]
Life, 2022 Retinal diseases, such as diabetic retinopathy (DR), age-related macular degeneration (AMD), and retinopathy of prematurity (ROP), are some of the leading causes of blindness all over the world [...]
Zhongjie Fu +3 more
openaire +3 more sources
Glucocorticoids, metabolism and metabolic diseases [PDF]
Molecular and Cellular Endocrinology, 2007 Since the discovery of the beneficial effects of adrenocortical extracts for treating adrenal insufficiency more than 80 years ago, glucocorticoids (GC) and their cognate, intracellular receptor, the glucocorticoid receptor (GR) have been characterized as critical components of the delicate hormonal control system that determines energy homeostasis in ...
Vegiopoulos, Alexandros, Herzig, Stephan
openaire +3 more sources