Results 231 to 240 of about 284,867 (287)

Synergistic All‐in‐One Electroceutical Platform Utilizing a Plasma–Photodynamic Hybrid Approach for Enhanced Wound Healing

Advanced Functional Materials, EarlyView.
A flexible hybrid patch integrating a robust cold atmospheric plasma (CAP) system with a high‐power, ultrathin bio‐OLED was developed to enable synergistic wound healing. This multimodal therapy, combining plasma and photodynamic treatment, enhanced angiogenesis, cell proliferation, and collagen deposition, demonstrating superior in vivo efficacy and ...
Jun‐Yeop Song, Hyun Cheol Bang, Young Hyun Son, Dae‐In Ha, Eun‐Ju Hong, Sun‐Woo Lee, Jeongsook Kim, Doyeong Kim, Sang‐Min Park, Kyu Pil Lee, Hyo‐Jung Kwon, Jeong Hyun Kwon   +11 more
wiley   +1 more source

Amyloidogenic Peptide Fragments Designed From Bacterial Collagen‐like Proteins Form Hydrogel

Advanced Functional Materials, EarlyView.
This study identified amyloidogenic sequence motifs in bacterial collagen‐like proteins and exploited these to design peptides that self‐assemble into β‐sheet fibers and form hydrogels. One hydrogel supported healthy fibroblast growth, showing promise for biocompatible materials. Our work demonstrates that bacterial sequences can be harnessed to create
Vamika Sagar, Xuen J Ng, Lukas Lechel, Ashish Chand Rajwar, Hendrik Bargel, Abhishek A. Jalan   +5 more
wiley   +1 more source

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Metabolic flux analysis in eukaryotes

Current Opinion in Biotechnology, 2010
Metabolic flux analysis (MFA) represents a powerful tool for systems biology research on eukaryotic cells. This review describes recent advances, the challenges as well as applications of metabolic flux analysis comprising fungi, mammalian cells and plants.
Jens, Niklas, Konstantin, Schneider, Elmar, Heinzle   +2 more
openaire   +2 more sources

Genetically constrained metabolic flux analysis

Metabolic Engineering, 2005
Significant progress has been made in using existing metabolic databases to estimate metabolic fluxes. Traditional metabolic flux analysis generally starts with a predetermined metabolic network. This approach has been employed successfully to analyze the behaviors of recombinant strains by manually adding or removing the corresponding pathway(s) in ...
Steven J, Cox, Sagit, Shalel Levanon, George N, Bennett, Ka-Yiu, San   +3 more
openaire   +2 more sources

13C Metabolic Flux Analysis

Metabolic Engineering, 2001
Metabolic flux analysis using 13C-labeled substrates has become an important tool in metabolic engineering. It allows the detailed quantification of all intracellular fluxes in the central metabolism of a microorganism. The method has strongly evolved in recent years by the introduction of new experimental procedures, measurement techniques, and ...
openaire   +2 more sources

Metabolic Flux Analysis and Visualization

Journal of Proteome Research, 2011
One of the ultimate goals of systems biology research is to obtain a comprehensive understanding of the control mechanisms of complex cellular metabolisms. Metabolic Flux Analysis (MFA) is a important method for the quantitative estimation of intracellular metabolic flows through metabolic pathways and the elucidation of cellular physiology.
Yoshihiro, Toya, Nobuaki, Kono, Kazuharu, Arakawa, Masaru, Tomita   +3 more
openaire   +2 more sources

Metabolic flux analysis in biotechnology processes

Biotechnology Letters, 2008
Metabolic flux analysis (MFA) has become a fundamental tool of metabolic engineering to elucidate the metabolic state of the cell and has been applied to various biotechnological processes. In recent years, considerable technical advances have been made.
Shintaro, Iwatani, Yohei, Yamada, Yoshihiro, Usuda   +2 more
openaire   +2 more sources

Metabolic flux analysis and metabolic engineering of microorganisms

Mol. BioSyst., 2008
Recent advances in metabolic flux analysis including genome-scale constraints-based flux analysis and its applications in metabolic engineering are reviewed. Various computational aspects of constraints-based flux analysis including genome-scale stoichiometric models, additional constraints used for the improved accuracy, and several algorithms for ...
Kim, Hyun Uk, Kim, Tae Yong, Lee, Sang Yup   +2 more
openaire   +3 more sources

Mass spectrometry for metabolic flux analysis

Biotechnology & Bioengineering, 1999
Mass spectrometry in combination with tracer experiments based on 13C substrates can serve as a powerful tool for the modeling and analysis of intracellular fluxes and the investigation of biochemical networks. The theoretical background for the application of mass spectrometry to metabolic flux analysis is discussed.
, Wittmann, , Heinzle
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Metabolic flux analysis and pharmaceutical production

Metabolic Engineering, 2010
Rational engineering of biological systems is an inherently complex process due to their evolved nature. Metabolic engineering emerged and developed over the past 20 years as a field in which methodologies for the rational engineering of biological systems is now being applied to specific industrial, medical, or scientific problems.
Brett A, Boghigian, Gargi, Seth, Robert, Kiss, Blaine A, Pfeifer   +3 more
openaire   +2 more sources