Results 131 to 140 of about 898,161 (347)

Prebiotic metabolic networks?

Molecular Systems Biology, 2014
A prebiotic origin of metabolism has been proposed as one of several scenarios for the origin of life. In their recent work, Ralser and colleagues (Keller et al, ) observe an enzyme‐free, metabolism‐like reaction network under conditions reproducing a possible prebiotic environment.
openaire   +3 more sources

Additional file 12 of Proteomics data analysis using multiple statistical approaches identified proteins and metabolic networks associated with sucrose accumulation in sugarcane

, 2022
Ao‐Mei Li, Zhong‐Liang Chen, Cui‐Xian Qin, Zi-Tong Li, Fen Liao, Mingqiao Wang, Prakash Lakshmanan, Yang‐Rui Li, Miao Wang, You-Qiang Pan, Dongliang Huang   +10 more
openalex   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

SurreyFBA: a command line tool and graphics user interface for constraint-based modeling of genome-scale metabolic reaction networks [PDF]

, 2010
Albert Gevorgyan, Michael E. Bushell, Claudio Avignone–Rossa, Andrzej Kierzek   +3 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Detecting and investigating substrate cycles in a genome‐scale human metabolic network [PDF]

, 2012
Juliane Gebauer, Stefan Schuster, Luís F. de Figueiredo, Christoph Kaleta   +3 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Identification of crucial nodes in biological networks [PDF]

Network Biology, 2012
This study showed that the crucial nodes in biological networks could be identified with network communities.
DeWu Ding
doaj  

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Geometric algorithms for sampling the flux space of metabolic networks

, 2022
Apostolos Chalkis, Vissarion Fisikopoulos, Elias Tsigaridas, Haris Zafeiropoulos   +3 more
openalex   +2 more sources