Results 161 to 170 of about 898,161 (347)

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu, Oliver Robinson, Christina M. Lill, Anna Matton, Raquel Puerta, Pilar Sanz, Merce Boada, Agustín Ruiz, Lefkos Middleton, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
wiley   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Functional profiling and visualization of the sphingolipid metabolic network in vivo. [PDF]

EMBO Rep
Tzou FY, Hong CL, Chen KH, Vaughen JP, Lin WS, Hsu CH, Rivas-Serna IM, Hsu KY, Ho SM, Panganiban MR, Hsieh HT, Li YJ, Hsiao Y, Yeh HC, Yu CY, Tang HW, Chou YH, Wu CL, Lo CC, Mazurak VC, Clandinin MT, Huang SY, Chan CC.   +22 more
europepmc   +1 more source

Global probabilistic annotation of metabolic networks enables enzyme discovery

, 2012
Germán Plata, Tobias Fuhrer, Tzu‐Lin Hsiao, Uwe Sauer, Dennis Vitkup   +4 more
openalex   +2 more sources

The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma, Ilo Leppik, Thomas Henry, Thaddeus Walczak, Sima Patel, Robert McGovern   +5 more
wiley   +1 more source

Emergence of metabolic-like cycles in blockchain-orchestrated reaction networks [PDF]

Rafał Roszak, Agnieszka Wołos, Marcin Benke, Łukasz Gleń, Jakub Konka, Phillip Jensen, Paweł Burgchardt, Anna Żądło‐Dobrowolska, Piotr Janiuk, Sara Szymkuć, Bartosz A. Grzybowski   +10 more
openalex   +1 more source

A comprehensive statistical study of metabolic and protein–protein interaction network properties [PDF]

, 2019
D. Gamermann, Julián Triana-Dopico, R. Jaime   +2 more
openalex   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Lipid metabolism orchestrates liver regeneration: an integrated metabolic network. [PDF]

J Transl Med
Duan L, Chang Y, Dai J, Lu H, Zhao W, Shen Y, Lin J, Cai X.   +7 more
europepmc   +1 more source